Cellular Defense against UVB-Induced Phototoxicity by Cytosolic NADP+-Dependent Isocitrate Dehydrogenase

Ultraviolet (UV) radiation is known as a major cause of skin photoaging and photocarcinogenesis. Many harmful effects of UV radiation are associated with the generation of reactive oxygen species. Recently, we have shown that NADP+-dependent isocitrate dehydrogenase is involved in the supply of NADP...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2002-03, Vol.292 (2), p.542-549
Hauptverfasser:	Jo, Seung-Hee, Lee, So-Hyun, Suk Chun, Hang, Min Lee, Su, Koh, Ho-Jin, Lee, Sung-Eun, Chun, Jang-Soo, Park, Jeen-Woo, Huh, Tae-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Antioxidants - metabolism Cell Survival - radiation effects Cytoprotection Cytosol - enzymology DNA Damage Glutathione - metabolism GSH recycling isocitrate dehydrogenase Isocitrate Dehydrogenase - genetics Isocitrate Dehydrogenase - metabolism Lipid Peroxidation - radiation effects Mice NADPH Oxidative Stress reactive oxygen species Reactive Oxygen Species - metabolism Transfection ultraviolet radiation Ultraviolet Rays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!