Inhibiting the nucleus tractus solitarii extends cerebrovascular autoregulation during hypertension

Autoregulation maintains cerebral blood flow near basal levels as blood pressure increases, but vasodilation, breakthrough, occurs when hypertension exceeds the autoregulatory range. Loss of breakthrough after transection of baroreceptor nerves suggests that breakthrough is neurally mediated. We hyp...

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Veröffentlicht in:	Brain research 2002-03, Vol.931 (1), p.92-95
Hauptverfasser:	Talman, William T, Nitschke Dragon, Deidre
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Local - administration & dosage Anesthetics, Local - pharmacology Animals Arterial hypertension. Arterial hypotension Baroreflex Baroreflex - drug effects Baroreflex - physiology Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Breakthrough Cardiology. Vascular system Cerebral blood flow Cerebrovascular Circulation - physiology Experimental diseases Heart Rate - drug effects Homeostasis - physiology Hypertension - physiopathology Lidocaine Lidocaine - administration & dosage Lidocaine - pharmacology Male Medical sciences Medulla Microinjections Rat Rats Rats, Sprague-Dawley Solitary Nucleus - drug effects Solitary Nucleus - physiology
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