Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus

Integrin-mediated cell adhesion is central to cell survival, differentiation and motility. Many cell responses induced by integrins require both receptor occupancy and receptor aggregation, and appear to be regulated by both biochemical and biophysical means. Multidomain extracellular matrix molecul...

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Veröffentlicht in:Journal of cell science 2002-04, Vol.115 (Pt 7), p.1423-1433
Hauptverfasser: Koo, Lily Y, Irvine, Darrell J, Mayes, Anne M, Lauffenburger, Douglas A, Griffith, Linda G
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Sprache:eng
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