Gene Repair and Transposon‐Mediated Gene Therapy

The main strategy of gene therapy has traditionally been focused on gene augmentation. This approach typically involves the introduction of an expression system designed to express a specific protein in the transfected cell. Both the basic and clinical sciences have generated enough information to s...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2002-01, Vol.20 (2), p.105-118
Hauptverfasser:	Richardson, Paul D., Augustin, Lance B., Kren, Betsy T., Steer, Clifford J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chimeraplasty Chimeric RNA/DNA oligonucleotide DNA Repair - genetics DNA Transposable Elements - genetics DNA, Single-Stranded - genetics Gene repair Genetic Therapy - methods Genetic Therapy - trends Humans Oligonucleotides - genetics Single‐stranded oligonucleotide Sleeping Beauty transposon system Small fragment homologous replacement Transposases - genetics Triplex‐forming oligonucleotide
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