CRE-enhancer DNA decoy: a tumor target-based genetic tool

Enhancer DNA decoy oligonucleotides (ODNs) inhibit transcription by competing for transcription factors. A decoy ODN composed of the cAMP response element (CRE) inhibits CRE-directed gene transcription and tumor growth without affecting normal cell growth. We used DNA microarrays to analyze the glob...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2003-12, Vol.1002 (1), p.124-133
1. Verfasser:	Cho-Chung, Yoon S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gene Expression Profiling Liver - drug effects Mice Neoplasms - drug therapy Oligodeoxyribonucleotides - genetics Oligodeoxyribonucleotides - pharmacology Response Elements - drug effects Response Elements - genetics
Online-Zugang:	Volltext
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