Clinical study of endocrine therapy in stage B and C prostate cancer
To evaluate the usefulness of endocrine therapy for stage B and C prostate cancer, we carried out a retrospective study on overall survival rate, cause-specific survival, PSA recurrence-free rate, and their predictive factors in 118 patients with stage B prostate cancer, 61 with stage C prostate can...
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| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica 2003-11, Vol.49 (11), p.639-643 |
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| container_title | Hinyokika kiyo. Acta urologica Japonica |
| container_volume | 49 |
| creator | Uei, Takatoshi Okazaki, Hiroshi Nakamura, Toshiyuki Katou, Nobuo Suzuki, Kazuhiro Yamanaka, Hidetoshi |
| description | To evaluate the usefulness of endocrine therapy for stage B and C prostate cancer, we carried out a retrospective study on overall survival rate, cause-specific survival, PSA recurrence-free rate, and their predictive factors in 118 patients with stage B prostate cancer, 61 with stage C prostate cancer who underwent endocrine therapy at our department between 1985 and 2001. The cause-specific survival rate and PSA recurrence-free rate of stage B patients who underwent endocrine therapy were well, and they will take a good clinical course. Thus, in this stage of prostate cancer, aged patients and patients with complications may be good candidates for endocrine therapy. The cause-specific survival rate and PSA recurrence-free rate in the stage C patients who underwent endocrine therapy were significantly low. In stage C patients, endocrine therapy should be combined early with other methods such as radiotherapy. In the stage B patients who underwent endocrine therapy, PSA and Gleason score appeared to be associated with the cause-specific survival rate and PSA recurrence-free rate. |
| format | Article |
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The cause-specific survival rate and PSA recurrence-free rate of stage B patients who underwent endocrine therapy were well, and they will take a good clinical course. Thus, in this stage of prostate cancer, aged patients and patients with complications may be good candidates for endocrine therapy. The cause-specific survival rate and PSA recurrence-free rate in the stage C patients who underwent endocrine therapy were significantly low. In stage C patients, endocrine therapy should be combined early with other methods such as radiotherapy. 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In stage C patients, endocrine therapy should be combined early with other methods such as radiotherapy. 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| ispartof | Hinyokika kiyo. Acta urologica Japonica, 2003-11, Vol.49 (11), p.639-643 |
| issn | 0018-1994 |
| language | jpn |
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| source | MEDLINE; Open Access Titles of Japan |
| subjects | Aged Antineoplastic Agents, Hormonal - therapeutic use Disease-Free Survival Humans Male Neoplasm Staging Prognosis Prostatic Neoplasms - drug therapy Prostatic Neoplasms - mortality Prostatic Neoplasms - pathology Retrospective Studies Survival Rate |
| title | Clinical study of endocrine therapy in stage B and C prostate cancer |
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