Preimplantation genetic diagnosis for a couple with recurrent pregnancy loss and triploidy

BACKGROUND Triploidy may arise from fertilization of a mature haploid egg by two haploid sperm or by failure of meiotic divisions yielding a diploid gamete. We encountered a couple with habitual abortion, in which the last two fetuses were documented as viable triploid. METHODS To avoid dispermic pe...

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Veröffentlicht in:	Birth defects research. A Clinical and molecular teratology 2003-11, Vol.67 (11), p.946-950
Hauptverfasser:	Bar-Ami, Shalom, Seibel, Machelle M., Pierce, Kenneth E., Zilberstein, Moshe
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - genetics Adult Biological and medical sciences Birth control Chromosome Aberrations Diploidy Female Fertilization in Vitro - methods fluorescence in situ hybridization (FISH) Gynecology. Andrology. Obstetrics Humans In Situ Hybridization, Fluorescence in vitro fertilization (IVF) intracytoplasmic sperm injection (ICSI) Karyotyping Male Medical sciences Meiosis Oocytes - metabolism Ploidies Pregnancy Preimplantation Diagnosis preimplantation genetic diagnosis (PGD) Sperm Injections, Intracytoplasmic - methods Spermatozoa - pathology Spermatozoa - ultrastructure Sterility. Assisted procreation triploidy
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