Clinical and immunological studies on neonatal infectious pneumonia
To explore etiology, clinical manifestation and immunological changes of infectious pneumonia of neonates in Chengdu area. Serum specimens were collected from 111 infants with infectious pneumonia. Eight viral and mycoplasmal specific serum IgM antibodies were detected by enzyme linked immunosorbent...
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| Veröffentlicht in: | Zhonghua er ke za zhi 2003-12, Vol.41 (12), p.884-888 |
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| container_title | Zhonghua er ke za zhi |
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| creator | Chen, Chang-hui Ye, Chang-ning Li, Mao-jun Mao, Xiao-lan Qiu, Lian-fen Lai, De-ming Yang, Qian He, Hai-lan Chen, Li-na |
| description | To explore etiology, clinical manifestation and immunological changes of infectious pneumonia of neonates in Chengdu area.
Serum specimens were collected from 111 infants with infectious pneumonia. Eight viral and mycoplasmal specific serum IgM antibodies were detected by enzyme linked immunosorbent assay (ELISA); C reactive protein (CRP), total IgG and its subclasses, IgA and IgM were determined by rate scattered nephelometry; T lymphocyte subpopulations were detected by biotin-streptavidin-peroxidase method, and clinical and other laboratory data were analyzed.
(1) Etiological agents: specific serum IgM antibodies were positive in 40 of 111 cases (36.0%) with pneumonias. All the 30 control infants were negative for the specific serum IgM antibodies. Among 111 infants with infectious pneumonia, 20.7% had single viral or mycoplasmal infection, 40.5% had bacterial infection, 15.3% had viral and mycoplasmal infection with bacterial infection; 23.4% had infection with unknown agents. (2) The most common clinical |
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Serum specimens were collected from 111 infants with infectious pneumonia. Eight viral and mycoplasmal specific serum IgM antibodies were detected by enzyme linked immunosorbent assay (ELISA); C reactive protein (CRP), total IgG and its subclasses, IgA and IgM were determined by rate scattered nephelometry; T lymphocyte subpopulations were detected by biotin-streptavidin-peroxidase method, and clinical and other laboratory data were analyzed.
(1) Etiological agents: specific serum IgM antibodies were positive in 40 of 111 cases (36.0%) with pneumonias. All the 30 control infants were negative for the specific serum IgM antibodies. Among 111 infants with infectious pneumonia, 20.7% had single viral or mycoplasmal infection, 40.5% had bacterial infection, 15.3% had viral and mycoplasmal infection with bacterial infection; 23.4% had infection with unknown agents. (2) The most common clinical</description><identifier>ISSN: 0578-1310</identifier><identifier>PMID: 14723804</identifier><language>chi</language><publisher>China</publisher><subject>Antibodies, Bacterial - blood ; Antibodies, Viral - blood ; Bacterial Infections - complications ; C-Reactive Protein - analysis ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin M - blood ; Infant, Newborn ; Male ; Pneumonia - diagnosis ; Pneumonia - etiology ; Pneumonia - immunology ; T-Lymphocyte Subsets - immunology ; T-Lymphocyte Subsets - metabolism ; Virus Diseases - complications</subject><ispartof>Zhonghua er ke za zhi, 2003-12, Vol.41 (12), p.884-888</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14723804$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Chang-hui</creatorcontrib><creatorcontrib>Ye, Chang-ning</creatorcontrib><creatorcontrib>Li, Mao-jun</creatorcontrib><creatorcontrib>Mao, Xiao-lan</creatorcontrib><creatorcontrib>Qiu, Lian-fen</creatorcontrib><creatorcontrib>Lai, De-ming</creatorcontrib><creatorcontrib>Yang, Qian</creatorcontrib><creatorcontrib>He, Hai-lan</creatorcontrib><creatorcontrib>Chen, Li-na</creatorcontrib><title>Clinical and immunological studies on neonatal infectious pneumonia</title><title>Zhonghua er ke za zhi</title><addtitle>Zhonghua Er Ke Za Zhi</addtitle><description>To explore etiology, clinical manifestation and immunological changes of infectious pneumonia of neonates in Chengdu area.
Serum specimens were collected from 111 infants with infectious pneumonia. Eight viral and mycoplasmal specific serum IgM antibodies were detected by enzyme linked immunosorbent assay (ELISA); C reactive protein (CRP), total IgG and its subclasses, IgA and IgM were determined by rate scattered nephelometry; T lymphocyte subpopulations were detected by biotin-streptavidin-peroxidase method, and clinical and other laboratory data were analyzed.
(1) Etiological agents: specific serum IgM antibodies were positive in 40 of 111 cases (36.0%) with pneumonias. All the 30 control infants were negative for the specific serum IgM antibodies. Among 111 infants with infectious pneumonia, 20.7% had single viral or mycoplasmal infection, 40.5% had bacterial infection, 15.3% had viral and mycoplasmal infection with bacterial infection; 23.4% had infection with unknown agents. (2) The most common clinical</description><subject>Antibodies, Bacterial - blood</subject><subject>Antibodies, Viral - blood</subject><subject>Bacterial Infections - complications</subject><subject>C-Reactive Protein - analysis</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Humans</subject><subject>Immunoglobulin M - blood</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Pneumonia - diagnosis</subject><subject>Pneumonia - etiology</subject><subject>Pneumonia - immunology</subject><subject>T-Lymphocyte Subsets - immunology</subject><subject>T-Lymphocyte Subsets - metabolism</subject><subject>Virus Diseases - complications</subject><issn>0578-1310</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0lLxEAYRPugOMM4f0Fy8hbor9fMUYIbDHjRc-hVGnqJ6fTBf2_Q8VTweBRVV2iPuRx6oIB36Fhr0JgKxghm9AbtgElCB8z2aBxjyMGo2Klsu5BSyyWWz19S12aDq13JXXYlq3VjIXtn1lBa7ebsWio5qFt07VWs7njJA_p4enwfX_rz2_Pr-HDuZyBk7SnX3ml5OhHPrfNCUmWV1tyABUxAG8owKEExp5viiVDMG-s5EYO3mhF6QPd_vfNSvpqr65RCNS5Gtc1rdZLAAYTAm3h3EZtOzk7zEpJavqf_2_QHXwxUsg</recordid><startdate>200312</startdate><enddate>200312</enddate><creator>Chen, Chang-hui</creator><creator>Ye, Chang-ning</creator><creator>Li, Mao-jun</creator><creator>Mao, Xiao-lan</creator><creator>Qiu, Lian-fen</creator><creator>Lai, De-ming</creator><creator>Yang, Qian</creator><creator>He, Hai-lan</creator><creator>Chen, Li-na</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200312</creationdate><title>Clinical and immunological studies on neonatal infectious pneumonia</title><author>Chen, Chang-hui ; Ye, Chang-ning ; Li, Mao-jun ; Mao, Xiao-lan ; Qiu, Lian-fen ; Lai, De-ming ; Yang, Qian ; He, Hai-lan ; Chen, Li-na</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p122t-35bfeb7992f5def673adabb5c1d1021bc3401a6305392ff26a4fcdf5268fdb423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2003</creationdate><topic>Antibodies, Bacterial - blood</topic><topic>Antibodies, Viral - blood</topic><topic>Bacterial Infections - complications</topic><topic>C-Reactive Protein - analysis</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Humans</topic><topic>Immunoglobulin M - blood</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Pneumonia - diagnosis</topic><topic>Pneumonia - etiology</topic><topic>Pneumonia - immunology</topic><topic>T-Lymphocyte Subsets - immunology</topic><topic>T-Lymphocyte Subsets - metabolism</topic><topic>Virus Diseases - complications</topic><toplevel>online_resources</toplevel><creatorcontrib>Chen, Chang-hui</creatorcontrib><creatorcontrib>Ye, Chang-ning</creatorcontrib><creatorcontrib>Li, Mao-jun</creatorcontrib><creatorcontrib>Mao, Xiao-lan</creatorcontrib><creatorcontrib>Qiu, Lian-fen</creatorcontrib><creatorcontrib>Lai, De-ming</creatorcontrib><creatorcontrib>Yang, Qian</creatorcontrib><creatorcontrib>He, Hai-lan</creatorcontrib><creatorcontrib>Chen, Li-na</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhonghua er ke za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Chang-hui</au><au>Ye, Chang-ning</au><au>Li, Mao-jun</au><au>Mao, Xiao-lan</au><au>Qiu, Lian-fen</au><au>Lai, De-ming</au><au>Yang, Qian</au><au>He, Hai-lan</au><au>Chen, Li-na</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical and immunological studies on neonatal infectious pneumonia</atitle><jtitle>Zhonghua er ke za zhi</jtitle><addtitle>Zhonghua Er Ke Za Zhi</addtitle><date>2003-12</date><risdate>2003</risdate><volume>41</volume><issue>12</issue><spage>884</spage><epage>888</epage><pages>884-888</pages><issn>0578-1310</issn><abstract>To explore etiology, clinical manifestation and immunological changes of infectious pneumonia of neonates in Chengdu area.
Serum specimens were collected from 111 infants with infectious pneumonia. Eight viral and mycoplasmal specific serum IgM antibodies were detected by enzyme linked immunosorbent assay (ELISA); C reactive protein (CRP), total IgG and its subclasses, IgA and IgM were determined by rate scattered nephelometry; T lymphocyte subpopulations were detected by biotin-streptavidin-peroxidase method, and clinical and other laboratory data were analyzed.
(1) Etiological agents: specific serum IgM antibodies were positive in 40 of 111 cases (36.0%) with pneumonias. All the 30 control infants were negative for the specific serum IgM antibodies. Among 111 infants with infectious pneumonia, 20.7% had single viral or mycoplasmal infection, 40.5% had bacterial infection, 15.3% had viral and mycoplasmal infection with bacterial infection; 23.4% had infection with unknown agents. (2) The most common clinical</abstract><cop>China</cop><pmid>14723804</pmid><tpages>5</tpages></addata></record> |
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| language | chi |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Antibodies, Bacterial - blood Antibodies, Viral - blood Bacterial Infections - complications C-Reactive Protein - analysis Enzyme-Linked Immunosorbent Assay Female Humans Immunoglobulin M - blood Infant, Newborn Male Pneumonia - diagnosis Pneumonia - etiology Pneumonia - immunology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism Virus Diseases - complications |
| title | Clinical and immunological studies on neonatal infectious pneumonia |
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