Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases

We reported previously that sulfoquinovosyl diacylglycerol and sulfoquinovosyl monoacylglycerol (SQDG/SQMG) are potent inhibitors of mammalian DNA polymerases and DNA topoisomerase II, and can be potent immunosuppressive agents and anticancer chemotherapy agents [Matsumoto, Y., Sahara, H., Fujita T....

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Veröffentlicht in:	Lipids 2003-10, Vol.38 (10), p.1065-1074
Hauptverfasser:	Mizushina, Yoshiyuki, Maeda, Naoki, Kawasaki, Miho, Ichikawa, Hideki, Murakami, Chikako, Takemura, Masaharu, Xu, Xianai, Sugawara, Fumio, Fukumori, Yoshinobu, Yoshida, Hiromi, Sakaguchi, Kengo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-HIV Agents - pharmacology Anticancer properties Antineoplastic drugs Cattle Cell Line, Tumor Cell Survival - drug effects Cell Survival - physiology Chemotherapy Deoxyribonucleic acid Diglycerides DNA DNA polymerase DNA topoisomerase DNA topoisomerase (ATP-hydrolysing) DNA-directed DNA polymerase DNA-Directed DNA Polymerase - metabolism Dose-Response Relationship, Drug Emulsification Emulsions Enzyme Inhibitors - pharmacology Experiments Gastric cancer Glycolipids - pharmacology Growth inhibition Humans Immunosuppression Immunosuppressive agents Lipids Mammals Nucleic Acid Synthesis Inhibitors Proteins Rats Sulfolipids Transplantation
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