Emergence of Zoonotic Canine Leishmaniasis in the United States: Isolation and Immunohistochemical Detection of Leishmania infantum from Foxhounds from Virginia

Previously considered an exotic disease, canine leishmaniasis caused by Leishmania infantum has recently been detected within the foxhound population in the United States and parts of Canada. Leishmania infantum is the etiologic agent of visceral leishmaniasis in many areas of the world and dogs are...

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Veröffentlicht in:The Journal of eukaryotic microbiology 2003, Vol.50 (6), p.691-693
Hauptverfasser: ROSYPAL, ALEXA C, TROY, GREGORY C, ZAJAC, ANNE M, DUNCAN, ROBERT B, WAKI, KAYOKO, CHANG, K.-P, LINDSAY, DAVID S
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container_end_page 693
container_issue 6
container_start_page 691
container_title The Journal of eukaryotic microbiology
container_volume 50
creator ROSYPAL, ALEXA C
TROY, GREGORY C
ZAJAC, ANNE M
DUNCAN, ROBERT B
WAKI, KAYOKO
CHANG, K.-P
LINDSAY, DAVID S
description Previously considered an exotic disease, canine leishmaniasis caused by Leishmania infantum has recently been detected within the foxhound population in the United States and parts of Canada. Leishmania infantum is the etiologic agent of visceral leishmaniasis in many areas of the world and dogs are considered a major reservoir host for human Leishmania infections. Human visceral leishmaniasis has recently emerged as an opportunistic infection among individuals co-infected with HIV/AIDS and in persons taking immunosuppressive drugs. We report the isolation of L. infantum from 3 naturally infected foxhounds from Virginia by culture of popliteal lymph node and bone marrow, and the development of an immunohistochemical test to detect the parasite in tissues.
doi_str_mv 10.1368/1066-5234(2003)050[0691:EOZCLI]2.0.CO;2
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source MEDLINE; Wiley-Blackwell Full Collection; BioOne Complete
subjects Animal protozoal diseases
Animals
Biological and medical sciences
Dog Diseases - parasitology
Dogs
Humans
Immunohistochemistry
Infectious diseases
Leishmania infantum - isolation & purification
Leishmaniasis, Visceral - transmission
Leishmaniasis, Visceral - veterinary
Medical sciences
Parasitic diseases
Protozoal diseases
Virginia
Zoonoses
title Emergence of Zoonotic Canine Leishmaniasis in the United States: Isolation and Immunohistochemical Detection of Leishmania infantum from Foxhounds from Virginia
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