Frequency and Determinants of Vitamin A Deficiency in Children Under 5 Years of Age with Pneumonia

Vitamin A deficiency (VAD) has been closely related to acute respiratory infections (ARI), although information is still incomplete; for example, the frequency of VAD in children

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Veröffentlicht in:Archives of medical research 2002-03, Vol.33 (2), p.180-185
Hauptverfasser: Reyes, Hortensia, Villalpando, Salvador, Pérez-Cuevas, Ricardo, Rodrı́guez, Leticia, Pérez-Cuevas, Miriam, Montalvo, Irene, Guiscafré, Héctor
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container_end_page 185
container_issue 2
container_start_page 180
container_title Archives of medical research
container_volume 33
creator Reyes, Hortensia
Villalpando, Salvador
Pérez-Cuevas, Ricardo
Rodrı́guez, Leticia
Pérez-Cuevas, Miriam
Montalvo, Irene
Guiscafré, Héctor
description Vitamin A deficiency (VAD) has been closely related to acute respiratory infections (ARI), although information is still incomplete; for example, the frequency of VAD in children
doi_str_mv 10.1016/S0188-4409(01)00361-7
format Article
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This study was conducted to gain insight into the status of vitamin A in children with pneumonia. A secondary objective was to identify the sociodemographic, individual, and nutritional factors associated with VAD in these children. A cross-sectional study was conducted in the Mexican state of Hidalgo, one of the poorest in the country. Children with community-acquired pneumonia treated at nine public hospitals were included. Information was obtained by interviewing mothers, and ascertainment of vitamin A status was performed with relative-dose-response (RDR) test. A total of 422 cases were included. VAD was identified in 17.8% of children; 50.3% showed normal results, 24.6% had liver reserve depletion, and 7.3% showed results attributable to the infectious process. Variables associated with VAD were as follows: age &lt;2 months (OR 3.44, 95% CI: 1.84–9.24); children &gt;6 months of age fed with formula (OR 0.37, 95% CI: 0.15–0.91), and affiliation with the Mexican Social Security Institute (IMSS) health system (OR 0.40, 95% CI: 0.22–0.72). The frequency of VAD in children with community-acquired pneumonia confirms that the problem of deficiency persists in Mexico. The associated factors for VAD found in this study can be taken into account when planning and evaluating vitamin A supplementation activities in populations with high risk for deficiency.</description><identifier>ISSN: 0188-4409</identifier><identifier>EISSN: 1873-5487</identifier><identifier>DOI: 10.1016/S0188-4409(01)00361-7</identifier><identifier>PMID: 11886719</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Child, Preschool ; Children ; Cross-Sectional Studies ; Female ; Humans ; Infant ; Liver - metabolism ; Male ; Mexico ; Pneumonia ; Pneumonia - complications ; Relative-dose-response test ; Risk factors ; Vitamin A - administration &amp; dosage ; Vitamin A - blood ; Vitamin A deficiency ; Vitamin A Deficiency - complications ; Vitamin A Deficiency - epidemiology</subject><ispartof>Archives of medical research, 2002-03, Vol.33 (2), p.180-185</ispartof><rights>2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c413t-f85f75b61ac4336684654197364700618b530b2e8ab1d681673328f62d4e57153</citedby><cites>FETCH-LOGICAL-c413t-f85f75b61ac4336684654197364700618b530b2e8ab1d681673328f62d4e57153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0188440901003617$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11886719$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reyes, Hortensia</creatorcontrib><creatorcontrib>Villalpando, Salvador</creatorcontrib><creatorcontrib>Pérez-Cuevas, Ricardo</creatorcontrib><creatorcontrib>Rodrı́guez, Leticia</creatorcontrib><creatorcontrib>Pérez-Cuevas, Miriam</creatorcontrib><creatorcontrib>Montalvo, Irene</creatorcontrib><creatorcontrib>Guiscafré, Héctor</creatorcontrib><title>Frequency and Determinants of Vitamin A Deficiency in Children Under 5 Years of Age with Pneumonia</title><title>Archives of medical research</title><addtitle>Arch Med Res</addtitle><description>Vitamin A deficiency (VAD) has been closely related to acute respiratory infections (ARI), although information is still incomplete; for example, the frequency of VAD in children &lt;5 years of age with pneumonia is not known, and the conditions associated with VAD have not been identified. This study was conducted to gain insight into the status of vitamin A in children with pneumonia. A secondary objective was to identify the sociodemographic, individual, and nutritional factors associated with VAD in these children. A cross-sectional study was conducted in the Mexican state of Hidalgo, one of the poorest in the country. Children with community-acquired pneumonia treated at nine public hospitals were included. Information was obtained by interviewing mothers, and ascertainment of vitamin A status was performed with relative-dose-response (RDR) test. A total of 422 cases were included. VAD was identified in 17.8% of children; 50.3% showed normal results, 24.6% had liver reserve depletion, and 7.3% showed results attributable to the infectious process. Variables associated with VAD were as follows: age &lt;2 months (OR 3.44, 95% CI: 1.84–9.24); children &gt;6 months of age fed with formula (OR 0.37, 95% CI: 0.15–0.91), and affiliation with the Mexican Social Security Institute (IMSS) health system (OR 0.40, 95% CI: 0.22–0.72). The frequency of VAD in children with community-acquired pneumonia confirms that the problem of deficiency persists in Mexico. The associated factors for VAD found in this study can be taken into account when planning and evaluating vitamin A supplementation activities in populations with high risk for deficiency.</description><subject>Child, Preschool</subject><subject>Children</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Mexico</subject><subject>Pneumonia</subject><subject>Pneumonia - complications</subject><subject>Relative-dose-response test</subject><subject>Risk factors</subject><subject>Vitamin A - administration &amp; dosage</subject><subject>Vitamin A - blood</subject><subject>Vitamin A deficiency</subject><subject>Vitamin A Deficiency - complications</subject><subject>Vitamin A Deficiency - epidemiology</subject><issn>0188-4409</issn><issn>1873-5487</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1vEzEQhi1ERUPbn1DkE4LD0pn4MycUBQpIlVqpFKkny7s72xplva29oeq_x9lEcOzJGs3zemYexk4RPiGgPrsGtLaSEhYfAD8CCI2VecVmaI2olLTmNZv9Qw7Z25x_A4CV2rxhh1ga2uBixurzRI8bis0z97HlX2ik1Ifo45j50PFfYfSl5MvS6UITJrDUq_uwbhNFfhNbSlzxW_JpSizviD-F8Z5fRdr0Qwz-mB10fp3pZP8esZvzrz9X36uLy28_VsuLqpEoxqqzqjOq1ugbKYTWZVUlcWGElgZAo62VgHpO1tfYaovaCDG3nZ63kpRBJY7Y-92_D2koJ-XR9SE3tF77SMMmu8KAlrAF1Q5s0pBzos49pND79OwQ3Faum-S6rTkH6Ca5zpTcu_2ATd1T-z-1t1mAzzuAypl_AiWXJ2XUhkTN6NohvDDiL0QihsE</recordid><startdate>20020301</startdate><enddate>20020301</enddate><creator>Reyes, Hortensia</creator><creator>Villalpando, Salvador</creator><creator>Pérez-Cuevas, Ricardo</creator><creator>Rodrı́guez, Leticia</creator><creator>Pérez-Cuevas, Miriam</creator><creator>Montalvo, Irene</creator><creator>Guiscafré, Héctor</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020301</creationdate><title>Frequency and Determinants of Vitamin A Deficiency in Children Under 5 Years of Age with Pneumonia</title><author>Reyes, Hortensia ; 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for example, the frequency of VAD in children &lt;5 years of age with pneumonia is not known, and the conditions associated with VAD have not been identified. This study was conducted to gain insight into the status of vitamin A in children with pneumonia. A secondary objective was to identify the sociodemographic, individual, and nutritional factors associated with VAD in these children. A cross-sectional study was conducted in the Mexican state of Hidalgo, one of the poorest in the country. Children with community-acquired pneumonia treated at nine public hospitals were included. Information was obtained by interviewing mothers, and ascertainment of vitamin A status was performed with relative-dose-response (RDR) test. A total of 422 cases were included. VAD was identified in 17.8% of children; 50.3% showed normal results, 24.6% had liver reserve depletion, and 7.3% showed results attributable to the infectious process. Variables associated with VAD were as follows: age &lt;2 months (OR 3.44, 95% CI: 1.84–9.24); children &gt;6 months of age fed with formula (OR 0.37, 95% CI: 0.15–0.91), and affiliation with the Mexican Social Security Institute (IMSS) health system (OR 0.40, 95% CI: 0.22–0.72). The frequency of VAD in children with community-acquired pneumonia confirms that the problem of deficiency persists in Mexico. The associated factors for VAD found in this study can be taken into account when planning and evaluating vitamin A supplementation activities in populations with high risk for deficiency.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>11886719</pmid><doi>10.1016/S0188-4409(01)00361-7</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Child, Preschool
Children
Cross-Sectional Studies
Female
Humans
Infant
Liver - metabolism
Male
Mexico
Pneumonia
Pneumonia - complications
Relative-dose-response test
Risk factors
Vitamin A - administration & dosage
Vitamin A - blood
Vitamin A deficiency
Vitamin A Deficiency - complications
Vitamin A Deficiency - epidemiology
title Frequency and Determinants of Vitamin A Deficiency in Children Under 5 Years of Age with Pneumonia
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