Ethnic Differences in the Associations between the HLA-DRB104 Subtypes and Type 1 Diabetes

: The HLA genotype DRB1*03,DQB1*0201/DRB1*04,DQB1*0302 confers a 25‐fold increase in the risk of type 1 diabetes. In persons with this genotype, DRB1*0405, *0402, and *0401 subtypes have been reported to further increase risk, whereas the *0403 and *0406 alleles confer a relative protection. We comp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of the New York Academy of Sciences 2003-11, Vol.1005 (1), p.301-309
Hauptverfasser:	REWERS, AMANDA, BABU, SUNANDA, WANG, TIAN BAO, BUGAWAN, TEODORICA L., BARRIGA, KATHY, EISENBARTH, GEORGE S., ERLICH, HENRY A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles autoimmune Case-Control Studies Child control development diabetes diabetes mellitus diabetes mellitus, insulin‐dependent Diabetes Mellitus, Type 1 - immunology disease epidemiology Ethnic Groups families first-degree relatives general population genetics genotype HLA-DQB1 HLA-DR Antigens - genetics HLA-DRB1 HLA-DRB1 Chains Humans IDDM insulin-dependent patients population protection risk type 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!