PULMONARY DEPOSITION OF MONODISPERSE AEROSOLS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

In order to improve patient convenience and drug availability for patients with α 1 -protease inhibitor deficiency, the administration via the inhalation route has been considered. This study investigated if it is possible to obtain high values of peripheral aerosol deposition by using optimized and...

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Veröffentlicht in:	Experimental lung research 2003-10, Vol.29 (7), p.475-484
Hauptverfasser:	Meyer, T., Müllinger, B., Sommerer, K., Scheuch, G., Brand, P., Beckmann, H., Häussinger, K., Weber, N., Siekmeier, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Aerosol Aerosols - administration & dosage Aerosols - pharmacokinetics alpha 1-Antitrypsin Deficiency - metabolism alpha 1-Antitrypsin Deficiency - physiopathology Biological and medical sciences Chronic Obstructive Pulmonary Disease Female Ferric Compounds Humans Inhalation Male Medical sciences Middle Aged Particle Size Peripheral Deposition Pharmacology. Drug treatments Pulmonary Alveoli - metabolism Pulmonary Disease, Chronic Obstructive - metabolism Pulmonary Disease, Chronic Obstructive - physiopathology Respiratory Function Tests Respiratory system Systemic Drug Delivery Technetium α 1 -proteinase Deficiency
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