Constitutive EGFR signaling confers a motile phenotype to neural stem cells

The epidermal growth factor receptor (EGFR) has been shown to play an important role in brain development, including stem and precursor cell survival, proliferation, differentiation, and migration. To further examine the temporal and spatial requirements of erbB signals in uncommitted neural stem ce...

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Veröffentlicht in:	Molecular and cellular neuroscience 2003-12, Vol.24 (4), p.1116-1130
Hauptverfasser:	Boockvar, John A, Kapitonov, Dmitri, Kapoor, Gurpreet, Schouten, Joost, Counelis, George J, Bogler, Oliver, Snyder, Evan Y, McIntosh, Tracy K, O'Rourke, Donald M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement - physiology Genes, erbB-1 - physiology Male Neurons - metabolism Phenotype Rats Rats, Sprague-Dawley Receptor, Epidermal Growth Factor - biosynthesis Receptor, Epidermal Growth Factor - genetics Signal Transduction - physiology Stem Cells - metabolism
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