Influence of a Terminal Formamido Group on the Sequence Recognition of DNA by Polyamides

Pyrrole (Py)-imidazole (Im)-containing polyamides bind in the minor groove of DNA and can recognize specific sequences through a stacked antiparallel dimer. It has been proposed that there are two different low energy ways to form the stacked dimer and that these are sensitive to the presence of a t...

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Veröffentlicht in:Journal of the American Chemical Society 2002-03, Vol.124 (10), p.2153-2163
Hauptverfasser: Lacy, Eilyn R, Le, N. Minh, Price, Carly A, Lee, Moses, Wilson, W. David
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Sprache:eng
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