Influence of a Terminal Formamido Group on the Sequence Recognition of DNA by Polyamides
Pyrrole (Py)-imidazole (Im)-containing polyamides bind in the minor groove of DNA and can recognize specific sequences through a stacked antiparallel dimer. It has been proposed that there are two different low energy ways to form the stacked dimer and that these are sensitive to the presence of a t...
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Veröffentlicht in: | Journal of the American Chemical Society 2002-03, Vol.124 (10), p.2153-2163 |
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Sprache: | eng |
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