Generation of adult‐like antibody avidity profiles after early‐life immunization with protein vaccines

The capacity to induce high‐avidity antibodies following early‐life immunization has long been questioned, and the possibility of inducing such antibodies soon after birth is a recognized goalfor a number of vaccination strategies. Therefore, we assessed the capacity to develop high‐avidity antibodi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of immunology 2002-03, Vol.32 (3), p.752-760
Hauptverfasser:	Schallert, Nadine, Pihlgren, Maria, Kovarik, Jiri, Roduit, Caroline, Tougne, Chantal, Bozzotti, Paola, Giudice, Giuseppe Del, Siegrist, Claire‐Anne, Lambert, Paul‐Henri
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - immunology Animals Animals, Suckling - immunology Antibodies, Bacterial - biosynthesis Antibodies, Bacterial - immunology Antibody Antibody Affinity Avidity B cell Bordetella pertussis - immunology Clostridium tetani - immunology Ficoll - analogs & derivatives Ficoll - immunology Immune System - growth & development Immunization Immunization Schedule Immunodominant Epitopes - immunology Immunoglobulin G - biosynthesis Immunoglobulin G - immunology Infant Mice Mice, Inbred BALB C Neonate Ovalbumin - immunology Peptide Fragments - immunology Specific Pathogen-Free Organisms Tetanus Toxoid - administration & dosage Tetanus Toxoid - immunology Toxoids - administration & dosage Toxoids - immunology Trinitrobenzenes - immunology Vaccines, Subunit - administration & dosage Vaccines, Subunit - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!