Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice

Chronic inflammatory responses involving the immune system have been implicated in the process of atherosclerosis. Sirolimus (Rapamycin, Rapamune®), a potent immunosuppressant used to prevent rejection of transplanted kidneys, has also proven effective at inhibiting restenosis in humans when eluted...

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Veröffentlicht in:	Transplantation proceedings 2003-12, Vol.35 (8), p.3136-3138
Hauptverfasser:	Basso, M.D, Nambi, P, Adelman, S.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - drug effects Aorta, Thoracic - metabolism Apolipoproteins E - deficiency Apolipoproteins E - genetics Biological and medical sciences Cholesterol - blood Drug toxicity and drugs side effects treatment Graft Occlusion, Vascular - prevention & control Humans Immunomodulators Immunosuppressive Agents - pharmacology Medical sciences Mice Mice, Knockout Miscellaneous (drug allergy, mutagens, teratogens...) Models, Animal Pharmacology. Drug treatments Sirolimus - pharmacology
Online-Zugang:	Volltext
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