Systemic Lupus Erythematosus Associated with Massive Ascites and Pleural Effusion in a Patient Who Presented with Disseminated Intravascular Coagulation
A case of systemic lupus erythematosus (SLE) associated with serositis presenting with disseminated intravascular coagulation (DIC) is reported. A 53-year-old woman was admitted because of a fever. Laboratory tests revealed increased plasma levels of fibrinogen degradation products (FDP) and FDP-D-d...
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| Veröffentlicht in: | Internal Medicine 2002, Vol.41(2), pp.161-166 |
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| creator | KAGEYAMA, Yo YAGI, Takashi MIYAIRI, Mamoru |
| description | A case of systemic lupus erythematosus (SLE) associated with serositis presenting with disseminated intravascular coagulation (DIC) is reported. A 53-year-old woman was admitted because of a fever. Laboratory tests revealed increased plasma levels of fibrinogen degradation products (FDP) and FDP-D-dimer, high titers of anti-nuclear antibody, high serum levels of anti-DNA antibody, immune complexes, decreased serum complements, and persistent proteinuria. A CT scan showed massive ascites and pleural effusion, marked edema and swelling of the mesenterium. The patient's condition and immunological abnormalities improved after steroid therapy. The association of DIC and lupus serositis has never been described in the literature. (Internal Medicine 41: 161-166, 2002) |
| doi_str_mv | 10.2169/internalmedicine.41.161 |
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A 53-year-old woman was admitted because of a fever. Laboratory tests revealed increased plasma levels of fibrinogen degradation products (FDP) and FDP-D-dimer, high titers of anti-nuclear antibody, high serum levels of anti-DNA antibody, immune complexes, decreased serum complements, and persistent proteinuria. A CT scan showed massive ascites and pleural effusion, marked edema and swelling of the mesenterium. The patient's condition and immunological abnormalities improved after steroid therapy. The association of DIC and lupus serositis has never been described in the literature. 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Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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Med.</addtitle><description>A case of systemic lupus erythematosus (SLE) associated with serositis presenting with disseminated intravascular coagulation (DIC) is reported. A 53-year-old woman was admitted because of a fever. Laboratory tests revealed increased plasma levels of fibrinogen degradation products (FDP) and FDP-D-dimer, high titers of anti-nuclear antibody, high serum levels of anti-DNA antibody, immune complexes, decreased serum complements, and persistent proteinuria. A CT scan showed massive ascites and pleural effusion, marked edema and swelling of the mesenterium. The patient's condition and immunological abnormalities improved after steroid therapy. The association of DIC and lupus serositis has never been described in the literature. (Internal Medicine 41: 161-166, 2002)</description><subject>Anorexia - etiology</subject><subject>anti-nuclear antibody</subject><subject>Antibodies, Antinuclear - blood</subject><subject>Ascites - etiology</subject><subject>Ascites - immunology</subject><subject>Autoimmune Diseases - blood</subject><subject>Autoimmune Diseases - complications</subject><subject>Autoimmune Diseases - diagnosis</subject><subject>Autoimmune Diseases - drug therapy</subject><subject>Biological and medical sciences</subject><subject>complement</subject><subject>Disseminated Intravascular Coagulation - etiology</subject><subject>Edema - etiology</subject><subject>Female</subject><subject>Fever - etiology</subject><subject>Fibrin Fibrinogen Degradation Products - analysis</subject><subject>Humans</subject><subject>immune complex</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Lupus Erythematosus, Systemic - blood</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Lupus Erythematosus, Systemic - diagnosis</subject><subject>Lupus Erythematosus, Systemic - drug therapy</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pleural Effusion - etiology</subject><subject>Prednisolone - therapeutic use</subject><subject>Purpura, Thrombocytopenic, Idiopathic - etiology</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>vasculitis</subject><subject>Vasculitis - etiology</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkc9u1DAQxi0EokvhFcAXuGWx4_yxj9WyQKVFrASIYzTrTLquEmfxOEX7Jn3cumxoJbiMx57ffDPyx9gbKZa5rMx75yMGD_2ArbPO47KQS1nJJ2whVWGyOlflU7YQRuosT-GMvSC6FkLp2uTP2ZmUutKVqBfs9tuRIg7O8s10mIivwzHucYA4UrpdEI3WQcSW_3Zxz78AkbvB9G5dROLgW77tcQrQ83XXTeRGz53nwLcQHfrIf-5Hvg1IKf8r8sERpYn-j-yljwFugOzUQ-CrEa5SEpPMS_asg57w1Xyesx8f199Xn7PN10-Xq4tNZstSxgx1jnkuWw2tVFoVValVKpiyxE5iocra7Apj7Q52lVGQSqLKW2OwVKYWAtQ5e3fSPYTx14QUm8GRxb4Hj-NETS0LXdeyTGB9Am0YiQJ2zSG4AcKxkaK5N6X515SmkE0yJXW-nkdMu1R77JtdSMDbGUgfAX0XwFtHj5yqKl3oInHbE3dNEa7wAYAQne3xvwWkMfn9EnNIuzygdg-hQa_uAAieutA</recordid><startdate>20020201</startdate><enddate>20020201</enddate><creator>KAGEYAMA, Yo</creator><creator>YAGI, Takashi</creator><creator>MIYAIRI, Mamoru</creator><general>The Japanese Society of Internal Medicine</general><general>Japanese Society of Internal Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020201</creationdate><title>Systemic Lupus Erythematosus Associated with Massive Ascites and Pleural Effusion in a Patient Who Presented with Disseminated Intravascular Coagulation</title><author>KAGEYAMA, Yo ; YAGI, Takashi ; MIYAIRI, Mamoru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c551t-e82e221d8ad138346583551955ef1e43579b49ccbab693a551062d99e539700a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Anorexia - etiology</topic><topic>anti-nuclear antibody</topic><topic>Antibodies, Antinuclear - blood</topic><topic>Ascites - etiology</topic><topic>Ascites - immunology</topic><topic>Autoimmune Diseases - blood</topic><topic>Autoimmune Diseases - complications</topic><topic>Autoimmune Diseases - diagnosis</topic><topic>Autoimmune Diseases - drug therapy</topic><topic>Biological and medical sciences</topic><topic>complement</topic><topic>Disseminated Intravascular Coagulation - etiology</topic><topic>Edema - etiology</topic><topic>Female</topic><topic>Fever - etiology</topic><topic>Fibrin Fibrinogen Degradation Products - analysis</topic><topic>Humans</topic><topic>immune complex</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Lupus Erythematosus, Systemic - blood</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Lupus Erythematosus, Systemic - diagnosis</topic><topic>Lupus Erythematosus, Systemic - drug therapy</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pleural Effusion - etiology</topic><topic>Prednisolone - therapeutic use</topic><topic>Purpura, Thrombocytopenic, Idiopathic - etiology</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>vasculitis</topic><topic>Vasculitis - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KAGEYAMA, Yo</creatorcontrib><creatorcontrib>YAGI, Takashi</creatorcontrib><creatorcontrib>MIYAIRI, Mamoru</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KAGEYAMA, Yo</au><au>YAGI, Takashi</au><au>MIYAIRI, Mamoru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Systemic Lupus Erythematosus Associated with Massive Ascites and Pleural Effusion in a Patient Who Presented with Disseminated Intravascular Coagulation</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2002-02-01</date><risdate>2002</risdate><volume>41</volume><issue>2</issue><spage>161</spage><epage>166</epage><pages>161-166</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A case of systemic lupus erythematosus (SLE) associated with serositis presenting with disseminated intravascular coagulation (DIC) is reported. A 53-year-old woman was admitted because of a fever. Laboratory tests revealed increased plasma levels of fibrinogen degradation products (FDP) and FDP-D-dimer, high titers of anti-nuclear antibody, high serum levels of anti-DNA antibody, immune complexes, decreased serum complements, and persistent proteinuria. A CT scan showed massive ascites and pleural effusion, marked edema and swelling of the mesenterium. The patient's condition and immunological abnormalities improved after steroid therapy. The association of DIC and lupus serositis has never been described in the literature. (Internal Medicine 41: 161-166, 2002)</abstract><cop>Tokyo</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>11868607</pmid><doi>10.2169/internalmedicine.41.161</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Anorexia - etiology anti-nuclear antibody Antibodies, Antinuclear - blood Ascites - etiology Ascites - immunology Autoimmune Diseases - blood Autoimmune Diseases - complications Autoimmune Diseases - diagnosis Autoimmune Diseases - drug therapy Biological and medical sciences complement Disseminated Intravascular Coagulation - etiology Edema - etiology Female Fever - etiology Fibrin Fibrinogen Degradation Products - analysis Humans immune complex Immunosuppressive Agents - therapeutic use Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - drug therapy Medical sciences Middle Aged Pleural Effusion - etiology Prednisolone - therapeutic use Purpura, Thrombocytopenic, Idiopathic - etiology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis vasculitis Vasculitis - etiology |
| title | Systemic Lupus Erythematosus Associated with Massive Ascites and Pleural Effusion in a Patient Who Presented with Disseminated Intravascular Coagulation |
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