The Cyclooxygenase-2 Inhibitor, Celecoxib, Prevents the Development of Mammary Tumors in HER-2/neu Mice
Evidence is now available showing that cyclooxygenase (COX)-2, which is involved in prostaglandin production, is overexpressed in many types of tumors including breast. Several reports have indicated that HER-2/ neu -positive breast tumors are associated with an increased amount of COX-2 protein. In...
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Veröffentlicht in: | Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2003-12, Vol.12 (12), p.1486-1491 |
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