Direct role of human dermal fibroblasts and indirect participation of epidermal keratinocytes in MMP-1 production after UV-B irradiation

In vivo, matrix metalloproteinases are produced in response to ultraviolet B (UV-B) irradiation and are considered to be involved in connective tissue alterations observed in photoaging. The respective roles of keratinocytes and fibroblasts in UV-B-induced MMP-1 production were investigated in monol...

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Veröffentlicht in:	Archives of Dermatological Research 2002-01, Vol.293 (11), p.576-583
Hauptverfasser:	FAGOT, Dominique, ASSELINEAU, Daniel, BERNERD, Francoise
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Biological and medical sciences Biological effects of radiation Coculture Techniques Culture Media - pharmacology Epidermal Cells Epidermis - drug effects Epidermis - metabolism Epidermis - radiation effects Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - radiation effects Fundamental and applied biological sciences. Psychology Humans Keratinocytes - drug effects Keratinocytes - metabolism Keratinocytes - radiation effects Matrix Metalloproteinase 1 - biosynthesis Mice Non ionizing radiations. Hertzian waves. Biooptics Skin - cytology Skin - drug effects Skin - metabolism Skin - radiation effects Tissues, organs and organisms biophysics Ultraviolet Rays
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