Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1–transformed T cells

Chemokines and chemokine receptors play important roles in migration and tissue localization of various lymphocyte subsets. Here, we report the highly frequent expression of CCR4 in adult T-cell leukemia (ATL) and human T-cell leukemia virus type 1 (HTLV-1)–immortalized T cells. Flow cytometric anal...

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Veröffentlicht in:	Blood 2002-03, Vol.99 (5), p.1505-1511
Hauptverfasser:	Yoshie, Osamu, Fujisawa, Ryuichi, Nakayama, Takashi, Harasawa, Hitomi, Tago, Hideaki, Izawa, Dai, Hieshima, Kunio, Tatsumi, Youichi, Matsushima, Kouji, Hasegawa, Hitoshi, Kanamaru, Akihisa, Kamihira, Shimeru, Yamada, Yasuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cell Line, Transformed Chemokines, CC - metabolism Chemokines, CC - pharmacology Chemotaxis, Leukocyte - drug effects Female Gene Products, tax - pharmacology Hematologic and hematopoietic diseases Human T-lymphotropic virus 1 Humans Jurkat Cells Leukemia-Lymphoma, Adult T-Cell - metabolism Leukemia-Lymphoma, Adult T-Cell - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Receptors, CCR4 Receptors, Chemokine - genetics Receptors, Chemokine - metabolism Receptors, Chemokine - physiology RNA, Messenger - drug effects Skin - metabolism Skin - pathology T-Lymphocytes - metabolism T-Lymphocytes - physiology T-Lymphocytes - virology
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