In situ analysis of solvents on breath and blood: a selected ion flow tube mass spectrometric study

We report measurements of residual vapour levels of xylenes and trimethylbenzenes, present following a floor re‐surfacing procedure, using the technique of selected ion flow tube mass spectrometry (SIFT‐MS). A subject exposed to controlled amounts of xylene and mesitylene was monitored by direct bre...

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Veröffentlicht in:	Rapid communications in mass spectrometry 2002-01, Vol.16 (5), p.427-432
Hauptverfasser:	Wilson, Paul F., Freeman, Colin G., McEwan, Murray J., Milligan, Daniel B., Allardyce, Randall A., Shaw, Geoffrey M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Algorithms Benzene Derivatives - analysis Breath Tests Humans Male Mass Spectrometry Polyurethanes - analysis Solvents - analysis Xylenes - analysis
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container_title	Rapid communications in mass spectrometry
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creator	Wilson, Paul F. Freeman, Colin G. McEwan, Murray J. Milligan, Daniel B. Allardyce, Randall A. Shaw, Geoffrey M.
description	We report measurements of residual vapour levels of xylenes and trimethylbenzenes, present following a floor re‐surfacing procedure, using the technique of selected ion flow tube mass spectrometry (SIFT‐MS). A subject exposed to controlled amounts of xylene and mesitylene was monitored by direct breath exhalation over a 4‐hour period after exposure to the volatile organic compounds (VOCs) had stopped. The headspace gases above 5‐mL blood samples taken over this period were also monitored. The decays of the solvent levels with time were fitted to a two‐compartment model with residence times for xylene and mesitylene of 0.37 h and 0.38 h, respectively (compartment one) and 2.5 h and 2.8 h, respectively (compartment two). Copyright © 2002 John Wiley & Sons, Ltd.
doi_str_mv	10.1002/rcm.594
format	Article
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Copyright © 2002 John Wiley & Sons, Ltd.</description><subject>Adult</subject><subject>Algorithms</subject><subject>Benzene Derivatives - analysis</subject><subject>Breath Tests</subject><subject>Humans</subject><subject>Male</subject><subject>Mass Spectrometry</subject><subject>Polyurethanes - analysis</subject><subject>Solvents - analysis</subject><subject>Xylenes - analysis</subject><issn>0951-4198</issn><issn>1097-0231</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E1v1DAQBmCrArXbFvEPkE_0UKX1xE6dcKsWKEVtQQjE0fJXRMCJtx6nZf89rrKCEyePNY9eaV5CXgI7A8bq82THs6YTe2QFrJMVqzk8IyvWNVAJ6NoDcoj4kzGApmb75ACgbaSs5YrY64nikGeqJx22OCCNPcUYHvyUyzxRk7zOP8raURNidG-opuiDt9k7OhTQh_hI82w8HTUixU1ZpTj6nAZLMc9ue0ye9zqgf7F7j8i39---rj9UN5-urteXN5XlDYjKarC-b3vWC2a59l1nHLSd1VKD1K7mreSt0U6YC10bAcbJp48tJ3EmasuPyOsld5Pi_ewxq3FA60PQk48zKglCdq2AAk8WaFNETL5XmzSMOm0VMPXUpyp9qtJnka92kbMZvfvndgUWcLqAxyH47f9y1Jf17RJXLXrA7H__1Tr9UheSy0Z9v7tS8hY-fm64VG_5H8NZjqk</recordid><startdate>20020101</startdate><enddate>20020101</enddate><creator>Wilson, Paul F.</creator><creator>Freeman, Colin G.</creator><creator>McEwan, Murray J.</creator><creator>Milligan, Daniel B.</creator><creator>Allardyce, Randall A.</creator><creator>Shaw, Geoffrey M.</creator><general>John Wiley & Sons, Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020101</creationdate><title>In situ analysis of solvents on breath and blood: a selected ion flow tube mass spectrometric study</title><author>Wilson, Paul F. ; Freeman, Colin G. ; McEwan, Murray J. ; Milligan, Daniel B. ; Allardyce, Randall A. ; Shaw, Geoffrey M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3514-ca1cef8f0f40c3ae99bd189ca7a17ad238738bad4b6a2b41bd7ad4bc5203042c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Algorithms</topic><topic>Benzene Derivatives - analysis</topic><topic>Breath Tests</topic><topic>Humans</topic><topic>Male</topic><topic>Mass Spectrometry</topic><topic>Polyurethanes - analysis</topic><topic>Solvents - analysis</topic><topic>Xylenes - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilson, Paul F.</creatorcontrib><creatorcontrib>Freeman, Colin G.</creatorcontrib><creatorcontrib>McEwan, Murray J.</creatorcontrib><creatorcontrib>Milligan, Daniel B.</creatorcontrib><creatorcontrib>Allardyce, Randall A.</creatorcontrib><creatorcontrib>Shaw, Geoffrey M.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rapid communications in mass spectrometry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilson, Paul F.</au><au>Freeman, Colin G.</au><au>McEwan, Murray J.</au><au>Milligan, Daniel B.</au><au>Allardyce, Randall A.</au><au>Shaw, Geoffrey M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In situ analysis of solvents on breath and blood: a selected ion flow tube mass spectrometric study</atitle><jtitle>Rapid communications in mass spectrometry</jtitle><addtitle>Rapid Commun. 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subjects	Adult Algorithms Benzene Derivatives - analysis Breath Tests Humans Male Mass Spectrometry Polyurethanes - analysis Solvents - analysis Xylenes - analysis
title	In situ analysis of solvents on breath and blood: a selected ion flow tube mass spectrometric study
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