Overexpression of Cyclooxygenase-2 Is Associated with Breast Carcinoma and Its Poor Prognostic Factors

Cyclooxygenase is the rate-limiting enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. The inducible form, cyclooxygenase-2, is known to be overexpressed in various human cancers including the colon, stomach, and urinary bladder. In this study, we evaluated the overexpressio...

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Veröffentlicht in:	Modern pathology 2003-12, Vol.16 (12), p.1199-1204
Hauptverfasser:	Shim, Jeong Yun, An, Hee Jung, Lee, Yong Hee, Kim, Seung Ki, Lee, Kyong Po, Lee, Kyong Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - enzymology Breast Neoplasms - pathology Carcinoma in Situ - enzymology Carcinoma in Situ - pathology Carcinoma, Intraductal, Noninfiltrating - enzymology Carcinoma, Intraductal, Noninfiltrating - pathology Colorectal cancer Cyclooxygenase 2 Enzymes Estrogens Female Humans Immunohistochemistry Isoenzymes - metabolism Laboratories Laboratory Medicine Lymph Nodes - pathology Lymphatic Metastasis Lymphatic system Medicine Medicine & Public Health Membrane Proteins Neoplasm Staging original-article Pathology Prognosis Prognostic factor Prostaglandin-Endoperoxide Synthases - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Tumorigenesis
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