Intraepidermal cells of paget’s carcinoma of the breast can be genetically different from those of the underlying carcinoma

Paget’s carcinoma (PC) of the breast is characterized by neoplastic cells of “glandular” type located within the epidermis of the nipple-areolar complex, often associated with an underlying ductal carcinoma, either in situ or invasive. At present the origin of PC cells is controversial, although the...

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Veröffentlicht in:	Human pathology 2003-12, Vol.34 (12), p.1321-1330
Hauptverfasser:	Morandi, Luca, Pession, Annalisa, Marucci, Gian Luca, Foschini, Maria Pia, Pruneri, Giancarlo, Viale, Giuseppe, Eusebi, Vincenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - analysis breast Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - pathology Cell Transformation, Neoplastic clonality Dermatology displacement loop DNA, Mitochondrial - genetics DNA, Neoplasm Female Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Loss of Heterozygosity Lymphatic Metastasis Male Mammary gland diseases Medical sciences Microdissection Middle Aged Mitochondrial DNA Mutation Paget's Disease, Mammary - genetics Paget's Disease, Mammary - pathology Paget’s carcinoma Polymerase Chain Reaction Sequence Analysis, DNA Tumors Tumors of the skin and soft tissue. Premalignant lesions
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