Norepinephrine metabolism in neuron: dissociation between 3,4-dihydroxyphenylglycol and 3,4-dihydroxymandelic acid pathways

To investigate the pre-synaptic metabolism of norepinephrine (NE), judged by variations in plasma concentration of 3,4-dihydroxyphenylglycol (DHPG) and 3,4-dihydroxymandelic acid (DOMA). Pithed and electrically stimulated (2.5 Hz) rats were given intravenous infusion of exogenous NE (6 nmol . kg-1 ....

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Veröffentlicht in:	Acta pharmacologica Sinica 2002-01, Vol.23 (1), p.59-65
Hauptverfasser:	Dong, Wen-Xin, Ni, Xiang-Lian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Clorgyline - pharmacology Cordotomy Desipramine - pharmacology Electric Stimulation Male Mandelic Acids - blood Methoxyhydroxyphenylglycol - analogs & derivatives Methoxyhydroxyphenylglycol - blood Monoamine Oxidase - metabolism Monoamine Oxidase Inhibitors - pharmacology Neurons - metabolism Norepinephrine - blood Norepinephrine - metabolism Norepinephrine - pharmacology Presynaptic Terminals - metabolism Rats
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