Cause of normal pulmonic velocity in fetal tetralogy of Fallot

In 10 fetuses with tetralogy of Fallot, 9 lacked high velocity across the obstructed right ventricular outflow tract, which we conclude was due to the parallel flow circulations created by the combination of ventricular septal defect and arterial duct. The normally high resistance in the fetal pulmo...

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Veröffentlicht in:The American journal of cardiology 2003-12, Vol.92 (12), p.1485-1487
Hauptverfasser: Guntheroth, Warren G., Forster, Fred K., Stevenson, J.Geoffrey
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container_issue 12
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container_title The American journal of cardiology
container_volume 92
creator Guntheroth, Warren G.
Forster, Fred K.
Stevenson, J.Geoffrey
description In 10 fetuses with tetralogy of Fallot, 9 lacked high velocity across the obstructed right ventricular outflow tract, which we conclude was due to the parallel flow circulations created by the combination of ventricular septal defect and arterial duct. The normally high resistance in the fetal pulmonary vascular system substantially exceeds the resistance of the systemic vasculature, resulting in the maintenance of right-to-left ductal flow in all 10 fetuses who had only moderate pulmonary obstruction.
doi_str_mv 10.1016/j.amjcard.2003.08.068
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Biological and medical sciences
Blood Flow Velocity - physiology
Cardiology. Vascular system
Cardiovascular disease
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Female
Fetal Diseases - diagnostic imaging
Fetal Diseases - physiopathology
Fetuses
Heart
Humans
Lungs
Medical sciences
Models, Cardiovascular
Pilot Projects
Pregnancy
Pulmonary Artery - diagnostic imaging
Pulmonary Artery - embryology
Pulmonary Artery - physiopathology
Tetralogy of Fallot - diagnostic imaging
Tetralogy of Fallot - embryology
Tetralogy of Fallot - physiopathology
Ultrasonography, Prenatal
Ventricular Outflow Obstruction - diagnostic imaging
Ventricular Outflow Obstruction - embryology
Ventricular Outflow Obstruction - physiopathology
title Cause of normal pulmonic velocity in fetal tetralogy of Fallot
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