Disruption of dystroglycan axis by β-dystroglycan processing in cardiomyopathic hamster muscle

α-Dystroglycan is a cell surface peripheral membrane protein which binds to the extracellular matrix, while β-dystroglycan is a type I integral membrane protein which anchors α-dystroglycan to the cell membrane via the N-terminal extracellular domain. The complex composed of α- and β-dystroglycan is...

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Veröffentlicht in:	Neuromuscular disorders : NMD 2003-12, Vol.13 (10), p.796-803
Hauptverfasser:	Matsumura, Kiichiro, Arai, Ken, Zhong, Di, Saito, Fumiaki, Fukuta-Ohi, Hiroko, Maekawa, Ryuji, Yamada, Hiroki, Shimizu, Teruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Cardiomyopathic hamster Cardiomyopathies - metabolism Cardiomyopathies - pathology Cardiomyopathies - physiopathology Cell Line Cell Membrane - metabolism Cricetinae Cytoskeletal Proteins - metabolism Dimerization Disease Models, Animal Dystroglycan Dystroglycans Extracellular matrix Extracellular Matrix - metabolism Macromolecular Substances Membrane Glycoproteins - metabolism Muscle, Skeletal - metabolism Muscle, Skeletal - pathology Muscle, Smooth - metabolism Muscle, Smooth - pathology Muscles - metabolism Muscles - pathology Muscles - physiopathology Myocardium - metabolism Myocardium - pathology Peptide Hydrolases - metabolism Rats Sarcoglycanopathy
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