Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK
Background: The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) criteria have been used to assess surgical risk in patients in the UK. The aim was to determine how applicable these criteria are to patients undergoing surgery in the USA. Methods: Two...
Gespeichert in:
| Veröffentlicht in: | British journal of surgery 2003-12, Vol.90 (12), p.1593-1598 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1598 |
|---|---|
| container_issue | 12 |
| container_start_page | 1593 |
| container_title | British journal of surgery |
| container_volume | 90 |
| creator | Bennett-Guerrero, E. Hyam, J. A. Shaefi, S. Prytherch, D. R. Sutton, G. L. Weaver, P. C. Mythen, M. G. Grocott, M. P. Parides, M. K. |
| description | Background:
The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) criteria have been used to assess surgical risk in patients in the UK. The aim was to determine how applicable these criteria are to patients undergoing surgery in the USA.
Methods:
Two cohorts of patients undergoing major non‐cardiac surgery were followed prospectively in the USA (n = 1056) and the UK (n = 1539). Each patient was assigned a risk score for preoperative physiological status and operative severity using the established POSSUM criteria. Death in hospital was the primary outcome measure. For each patient a predicted risk of death was calculated from Portsmouth POSSUM (P‐POSSUM) methodology using an established equation. The relationships between predicted and observed mortality rates in each cohort were investigated by means of multivariate logistic regression.
Results:
Within each cohort, an increase in risk estimated by P‐POSSUM predicted an increase in observed mortality rate (P < 0·001). For any given risk level, however, mortality rates were significantly higher in the UK cohort than in the US cohort (odds ratio 4·50 (95 per cent confidence interval 2·81 to 7·19); Z = 6·25, P < 0·001).
Conclusion:
An increase in predicted risk, based on the P‐POSSUM methodology, was associated with a higher mortality rate in patients from both countries. However, risk‐adjusted mortality rates following major surgery were four times higher in the UK cohort. These marked differences warrant validation in a larger number of centres. Copyright © 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
May shock surgeons in the UK |
| doi_str_mv | 10.1002/bjs.4347 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_71466509</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71466509</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4527-150ab7655d134183257a641bd9c89ab12e12a1686d5b1ddc2119bd654e281f8b3</originalsourceid><addsrcrecordid>eNpF0U1vEzEQBmALgWhakPgFyBe4bevx1-4e26gN0EIrQgQ3y157wel-BNurkn-PowRyGsvzyPLMi9AbIOdACL0w63jOGS-foRkwKQoKsnqOZoSQsgBG2Qk6jXFNCDAi6Et0AlzyquQwQ34-9hsdfBwHPLb4oXi4Xy5Xn3G-eSy0XU8xOYv7MSTd-bTFQScXsW6TCzhO4acLW2xcenJuwBudvBtSxH7A6ZfDq-Ul1oPdn29foRet7qJ7fahnaHVz_W3-obi7X3ycX94VDRc0f1cQbUophAXGoWJUlFpyMLZuqloboA6ozuNJKwxY21CA2lgpuKMVtJVhZ-j9_t1NGH9PLibV-9i4rtODG6eoyjy8FKTO8O0BTqZ3Vm2C73XYqn_LyeDdAejY6K4Nemh8PDrBKNQ1y67Yuyffue2xT9QuHJXDUbtw1NWn5a4evc_L_fPf6_CoZMlKob5_WajF_GtZc_5DXbG_3_COQg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71466509</pqid></control><display><type>article</type><title>Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><source>Oxford Journals - Connect here FIRST to enable access</source><creator>Bennett-Guerrero, E. ; Hyam, J. A. ; Shaefi, S. ; Prytherch, D. R. ; Sutton, G. L. ; Weaver, P. C. ; Mythen, M. G. ; Grocott, M. P. ; Parides, M. K.</creator><creatorcontrib>Bennett-Guerrero, E. ; Hyam, J. A. ; Shaefi, S. ; Prytherch, D. R. ; Sutton, G. L. ; Weaver, P. C. ; Mythen, M. G. ; Grocott, M. P. ; Parides, M. K.</creatorcontrib><description>Background:
The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) criteria have been used to assess surgical risk in patients in the UK. The aim was to determine how applicable these criteria are to patients undergoing surgery in the USA.
Methods:
Two cohorts of patients undergoing major non‐cardiac surgery were followed prospectively in the USA (n = 1056) and the UK (n = 1539). Each patient was assigned a risk score for preoperative physiological status and operative severity using the established POSSUM criteria. Death in hospital was the primary outcome measure. For each patient a predicted risk of death was calculated from Portsmouth POSSUM (P‐POSSUM) methodology using an established equation. The relationships between predicted and observed mortality rates in each cohort were investigated by means of multivariate logistic regression.
Results:
Within each cohort, an increase in risk estimated by P‐POSSUM predicted an increase in observed mortality rate (P < 0·001). For any given risk level, however, mortality rates were significantly higher in the UK cohort than in the US cohort (odds ratio 4·50 (95 per cent confidence interval 2·81 to 7·19); Z = 6·25, P < 0·001).
Conclusion:
An increase in predicted risk, based on the P‐POSSUM methodology, was associated with a higher mortality rate in patients from both countries. However, risk‐adjusted mortality rates following major surgery were four times higher in the UK cohort. These marked differences warrant validation in a larger number of centres. Copyright © 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
May shock surgeons in the UK</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.4347</identifier><identifier>PMID: 14648741</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Biological and medical sciences ; Cohort Studies ; Humans ; Medical sciences ; Miscellaneous ; Postoperative Complications - mortality ; Predictive Value of Tests ; Regression Analysis ; Risk Assessment ; Risk Factors ; Severity of Illness Index ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Survival Analysis ; Survival Rate ; United Kingdom - epidemiology ; United States - epidemiology</subject><ispartof>British journal of surgery, 2003-12, Vol.90 (12), p.1593-1598</ispartof><rights>Copyright © 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><rights>2004 INIST-CNRS</rights><rights>Copyright 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4527-150ab7655d134183257a641bd9c89ab12e12a1686d5b1ddc2119bd654e281f8b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.4347$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.4347$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15321993$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14648741$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bennett-Guerrero, E.</creatorcontrib><creatorcontrib>Hyam, J. A.</creatorcontrib><creatorcontrib>Shaefi, S.</creatorcontrib><creatorcontrib>Prytherch, D. R.</creatorcontrib><creatorcontrib>Sutton, G. L.</creatorcontrib><creatorcontrib>Weaver, P. C.</creatorcontrib><creatorcontrib>Mythen, M. G.</creatorcontrib><creatorcontrib>Grocott, M. P.</creatorcontrib><creatorcontrib>Parides, M. K.</creatorcontrib><title>Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) criteria have been used to assess surgical risk in patients in the UK. The aim was to determine how applicable these criteria are to patients undergoing surgery in the USA.
Methods:
Two cohorts of patients undergoing major non‐cardiac surgery were followed prospectively in the USA (n = 1056) and the UK (n = 1539). Each patient was assigned a risk score for preoperative physiological status and operative severity using the established POSSUM criteria. Death in hospital was the primary outcome measure. For each patient a predicted risk of death was calculated from Portsmouth POSSUM (P‐POSSUM) methodology using an established equation. The relationships between predicted and observed mortality rates in each cohort were investigated by means of multivariate logistic regression.
Results:
Within each cohort, an increase in risk estimated by P‐POSSUM predicted an increase in observed mortality rate (P < 0·001). For any given risk level, however, mortality rates were significantly higher in the UK cohort than in the US cohort (odds ratio 4·50 (95 per cent confidence interval 2·81 to 7·19); Z = 6·25, P < 0·001).
Conclusion:
An increase in predicted risk, based on the P‐POSSUM methodology, was associated with a higher mortality rate in patients from both countries. However, risk‐adjusted mortality rates following major surgery were four times higher in the UK cohort. These marked differences warrant validation in a larger number of centres. Copyright © 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
May shock surgeons in the UK</description><subject>Biological and medical sciences</subject><subject>Cohort Studies</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Postoperative Complications - mortality</subject><subject>Predictive Value of Tests</subject><subject>Regression Analysis</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Survival Analysis</subject><subject>Survival Rate</subject><subject>United Kingdom - epidemiology</subject><subject>United States - epidemiology</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0U1vEzEQBmALgWhakPgFyBe4bevx1-4e26gN0EIrQgQ3y157wel-BNurkn-PowRyGsvzyPLMi9AbIOdACL0w63jOGS-foRkwKQoKsnqOZoSQsgBG2Qk6jXFNCDAi6Et0AlzyquQwQ34-9hsdfBwHPLb4oXi4Xy5Xn3G-eSy0XU8xOYv7MSTd-bTFQScXsW6TCzhO4acLW2xcenJuwBudvBtSxH7A6ZfDq-Ul1oPdn29foRet7qJ7fahnaHVz_W3-obi7X3ycX94VDRc0f1cQbUophAXGoWJUlFpyMLZuqloboA6ozuNJKwxY21CA2lgpuKMVtJVhZ-j9_t1NGH9PLibV-9i4rtODG6eoyjy8FKTO8O0BTqZ3Vm2C73XYqn_LyeDdAejY6K4Nemh8PDrBKNQ1y67Yuyffue2xT9QuHJXDUbtw1NWn5a4evc_L_fPf6_CoZMlKob5_WajF_GtZc_5DXbG_3_COQg</recordid><startdate>200312</startdate><enddate>200312</enddate><creator>Bennett-Guerrero, E.</creator><creator>Hyam, J. A.</creator><creator>Shaefi, S.</creator><creator>Prytherch, D. R.</creator><creator>Sutton, G. L.</creator><creator>Weaver, P. C.</creator><creator>Mythen, M. G.</creator><creator>Grocott, M. P.</creator><creator>Parides, M. K.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200312</creationdate><title>Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK</title><author>Bennett-Guerrero, E. ; Hyam, J. A. ; Shaefi, S. ; Prytherch, D. R. ; Sutton, G. L. ; Weaver, P. C. ; Mythen, M. G. ; Grocott, M. P. ; Parides, M. K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4527-150ab7655d134183257a641bd9c89ab12e12a1686d5b1ddc2119bd654e281f8b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Biological and medical sciences</topic><topic>Cohort Studies</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Postoperative Complications - mortality</topic><topic>Predictive Value of Tests</topic><topic>Regression Analysis</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Survival Analysis</topic><topic>Survival Rate</topic><topic>United Kingdom - epidemiology</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bennett-Guerrero, E.</creatorcontrib><creatorcontrib>Hyam, J. A.</creatorcontrib><creatorcontrib>Shaefi, S.</creatorcontrib><creatorcontrib>Prytherch, D. R.</creatorcontrib><creatorcontrib>Sutton, G. L.</creatorcontrib><creatorcontrib>Weaver, P. C.</creatorcontrib><creatorcontrib>Mythen, M. G.</creatorcontrib><creatorcontrib>Grocott, M. P.</creatorcontrib><creatorcontrib>Parides, M. K.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bennett-Guerrero, E.</au><au>Hyam, J. A.</au><au>Shaefi, S.</au><au>Prytherch, D. R.</au><au>Sutton, G. L.</au><au>Weaver, P. C.</au><au>Mythen, M. G.</au><au>Grocott, M. P.</au><au>Parides, M. K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2003-12</date><risdate>2003</risdate><volume>90</volume><issue>12</issue><spage>1593</spage><epage>1598</epage><pages>1593-1598</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) criteria have been used to assess surgical risk in patients in the UK. The aim was to determine how applicable these criteria are to patients undergoing surgery in the USA.
Methods:
Two cohorts of patients undergoing major non‐cardiac surgery were followed prospectively in the USA (n = 1056) and the UK (n = 1539). Each patient was assigned a risk score for preoperative physiological status and operative severity using the established POSSUM criteria. Death in hospital was the primary outcome measure. For each patient a predicted risk of death was calculated from Portsmouth POSSUM (P‐POSSUM) methodology using an established equation. The relationships between predicted and observed mortality rates in each cohort were investigated by means of multivariate logistic regression.
Results:
Within each cohort, an increase in risk estimated by P‐POSSUM predicted an increase in observed mortality rate (P < 0·001). For any given risk level, however, mortality rates were significantly higher in the UK cohort than in the US cohort (odds ratio 4·50 (95 per cent confidence interval 2·81 to 7·19); Z = 6·25, P < 0·001).
Conclusion:
An increase in predicted risk, based on the P‐POSSUM methodology, was associated with a higher mortality rate in patients from both countries. However, risk‐adjusted mortality rates following major surgery were four times higher in the UK cohort. These marked differences warrant validation in a larger number of centres. Copyright © 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
May shock surgeons in the UK</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>14648741</pmid><doi>10.1002/bjs.4347</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1323 |
| ispartof | British journal of surgery, 2003-12, Vol.90 (12), p.1593-1598 |
| issn | 0007-1323 1365-2168 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71466509 |
| source | Wiley-Blackwell Journals; MEDLINE; Oxford Journals - Connect here FIRST to enable access |
| subjects | Biological and medical sciences Cohort Studies Humans Medical sciences Miscellaneous Postoperative Complications - mortality Predictive Value of Tests Regression Analysis Risk Assessment Risk Factors Severity of Illness Index Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Survival Analysis Survival Rate United Kingdom - epidemiology United States - epidemiology |
| title | Comparison of P-POSSUM risk-adjusted mortality rates after surgery between patients in the USA and the UK |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T08%3A44%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20P-POSSUM%20risk-adjusted%20mortality%20rates%20after%20surgery%20between%20patients%20in%20the%20USA%20and%20the%20UK&rft.jtitle=British%20journal%20of%20surgery&rft.au=Bennett-Guerrero,%20E.&rft.date=2003-12&rft.volume=90&rft.issue=12&rft.spage=1593&rft.epage=1598&rft.pages=1593-1598&rft.issn=0007-1323&rft.eissn=1365-2168&rft.coden=BJSUAM&rft_id=info:doi/10.1002/bjs.4347&rft_dat=%3Cproquest_pubme%3E71466509%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=71466509&rft_id=info:pmid/14648741&rfr_iscdi=true |