HLA in Czech adult patients with autoimmune diabetes mellitus: comparison with Czech children with type 1 diabetes and patients with type 2 diabetes

Summary Type 1 diabetes results from an autoimmune insulitis, associated with HLA class II alleles. The evidence about HLA allele association is not clear in patients diagnosed after 35 years of age. In this study we have analyzed HLA alleles of DQB1 and DRB1 genes by sequence specific primer (SSP)‐...

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Veröffentlicht in:	European journal of immunogenetics 2003-12, Vol.30 (6), p.401-407
Hauptverfasser:	Cerna, M., Novota, P., Kolostova, K., Cejkova, P., Zdarsky, E., Novakova, D., Kucera, P., Novak, J., Andel, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Aged Case-Control Studies Child Czech Republic Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - immunology Female Gene Frequency Genetic Predisposition to Disease HLA Antigens - genetics HLA-DQ Antigens - genetics HLA-DQ beta-Chains HLA-DR Antigens - genetics HLA-DR4 Antigen - genetics HLA-DRB1 Chains Humans Male Middle Aged
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