Efficacy of DA-8159, a new PDE5 inhibitor, for inducing penile erection in rabbits with acute spinal cord injury

DA-8159 is a pyrazolopyrimidinone derivative which exhibits potent and selective phosphodiesterase type 5 (PDE5) inhibition. The aim of this study was to investigate the effects of DA-8159 on inducing a penile erection in rabbits with an acute spinal cord injury (ASCI). DA-8159 was given either oral...

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Veröffentlicht in:	International journal of impotence research 2003-12, Vol.15 (6), p.405-411
Hauptverfasser:	AHN, B. O, KANG, K. K, AHN, G. J, KWON, J. W, KIM, W. B, KANG, K.-S, LEE, Y.-S
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-GMP Phosphodiesterases - antagonists & inhibitors Acute Disease Animals Area Under Curve Biological and medical sciences Cyclic Nucleotide Phosphodiesterases, Type 5 Disease Models, Animal Erectile dysfunction Erectile Dysfunction - drug therapy Erectile Dysfunction - etiology Gynecology. Andrology. Obstetrics Male Male genital diseases Medical sciences Nitric oxide Non tumoral diseases Penile Erection - drug effects Penile Erection - physiology Penis Pyrimidines - pharmacology Rabbits Reperfusion Injury - drug therapy Spinal Cord - pathology Spinal cord injuries Spinal Cord Injuries - complications Spinal Cord Injuries - pathology Sulfonamides Urological surgery
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