Phenylalanine-binding RNAs and genetic code evolution

We isolated RNAs by selection-amplification, selecting for affinity to Phe-Sepharose and elution with free l-phenylalanine. Constant sequences did not contain Phe condons or anticodons, to avoid any possible confounding influence on initially randomized sequences. We examined the eight most frequent...

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Veröffentlicht in:	Journal of molecular evolution 2002-03, Vol.54 (3), p.298-311
Hauptverfasser:	Illangasekare, Mali, Yarus, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Base Sequence Binding sites Binding Sites - genetics Chromatography, Affinity Evolution, Molecular Evolutionary biology Genetic Code - genetics Genetics Humans Molecular Sequence Data Phenylalanine - metabolism Ribonucleic acid RNA RNA - genetics RNA - metabolism Sequence Analysis, RNA Thermodynamics
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