The Concentration of Serum Transforming Growth Factor Beta-1 (TGF-β1) Is Decreased in Cervical Carcinoma Patients

Transforming growth factor beta-1 (TGF-β1) is a multifunctional growth factor and known to inhibit the proliferation of epithelial cell. The relationship between serum TGF-β1 level and the presence of cervical cancer was investigated in this study. The patients with cervical squamous cell carcinoma...

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Veröffentlicht in:	Cancer investigation 2002, Vol.20 (1), p.55-59
Hauptverfasser:	Wu, Hwa-Shyi, Li, Ywan Feng, Chou, Chuan-I, Yuan, Chiou Chung, Hung, Mei Whey, Tsai, Lai Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Squamous Cell - blood Cell Differentiation Down-Regulation Enzyme-Linked Immunosorbent Assay Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Medical sciences Middle Aged Transforming Growth Factor beta - blood Transforming Growth Factor beta1 Tumors Uterine Cervical Neoplasms - blood
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Zusammenfassung:	Transforming growth factor beta-1 (TGF-β1) is a multifunctional growth factor and known to inhibit the proliferation of epithelial cell. The relationship between serum TGF-β1 level and the presence of cervical cancer was investigated in this study. The patients with cervical squamous cell carcinoma (SCC) had significantly lower level of serum TGF-β1 (39.14±9.03 ng mL; mean ± SD) than those with myoma (49.17±9.38 ng mL) and normal subjects (49.13±8.81 ng mL), (p
ISSN:	0735-7907 1532-4192
DOI:	10.1081/CNV-120000366