Inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 reverse transcriptase, protease and integrase

A variety of antifungal proteins were isolated from seeds of leguminous plants including French bean, cowpea, field bean, mung bean, peanut and red kidney bean. They were assayed for ability to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase, protease and integrase, enzymes...

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Veröffentlicht in:	Life sciences (1973) 2002-01, Vol.70 (8), p.927-935
Hauptverfasser:	Ng, T.B., Au, T.K., Lam, T.L., Ye, X.Y., Wan, D.C.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Anti-HIV Agents - isolation & purification Anti-HIV Agents - pharmacology Anti-HIV enzymes Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Antifungal proteins Enzyme-Linked Immunosorbent Assay Fabaceae - chemistry HIV Integrase - drug effects HIV Protease - drug effects HIV Reverse Transcriptase - antagonists & inhibitors HIV-1 - drug effects Human immunodeficiency virus 1 Molecular Sequence Data Plant Proteins - isolation & purification Plant Proteins - pharmacology Seeds - chemistry
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