Effect of Previous or Simultaneous Immunization with Canarypox Expressing Cytomegalovirus (CMV) Glycoprotein B (gB) on Response to Subunit gB Vaccine plus MF59 in Healthy CMV-Seronegative Adults

Development of a vaccine for prevention of congenital cytomegalovirus (CMV) disease is a priority. This study evaluated a “prime-boost” strategy by comparing the safety and immunogenicity of 3 doses of subunit CMV glycoprotein B (gB) vaccine plus MF59 (a squalene-in-water emulsion), 2 doses of a can...

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Veröffentlicht in:	The Journal of infectious diseases 2002-03, Vol.185 (5), p.686-690
Hauptverfasser:	Bernstein, David I., Schleiss, Mark R., Berencsi, Klara, Gonczol, Eva, Dickey, Michelle, Khoury, Phil, Cadoz, Michel, Meric, Claude, Zahradnik, John, Duliege, Anne-Marie, Plotkin, Stanley
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Adolescent Adult Antibodies Antibodies, Viral - blood Bacteriology Biological and medical sciences Concise Communication Cytomegalovirus Cytomegalovirus infections Cytomegalovirus Infections - prevention & control Cytomegalovirus Vaccines - administration & dosage Cytomegalovirus Vaccines - immunology Dosage Enzyme linked immunosorbent assay Fundamental and applied biological sciences. Psychology Glycoproteins Humans Immunization Immunization Schedule Immunization, Secondary Lymphocyte Activation Microbiology Middle Aged Pain Placebos Polysorbates - administration & dosage Squalene - administration & dosage Squalene - immunology Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Subunit - administration & dosage Vaccines, Subunit - immunology Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Viral Envelope Proteins - genetics Viral Envelope Proteins - immunology Viral Envelope Proteins - metabolism Viral Vaccines - administration & dosage Viral Vaccines - genetics Viral Vaccines - immunology Virology
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