Telomere shortening in patients with plasma cell disorders

: Objectives: Telomeres are essential for maintaining chromosomal integrity; their shortening is associated with chromosome instability. The aim of this work was to study telomere length (TL) on bone marrow (BM) cells from patients with multiple myeloma (MM) and monoclonal gammopathy of undetermined...

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Veröffentlicht in:	European journal of haematology 2003-11, Vol.71 (5), p.334-340
Hauptverfasser:	Cottliar, Alejandra, Pedrazzini, Estela, Corrado, Claudia, Engelberger, María Inés, Narbaitz, Marina, Slavutsky, Irma
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bone Marrow - pathology Chromosome Aberrations Disease Progression Female Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology In Situ Hybridization, Fluorescence Karyotyping Male Medical sciences monoclonal gammopathy of undetermined significance multiple myeloma Multiple Myeloma - genetics Multiple Myeloma - pathology Paraproteinemias - genetics Paraproteinemias - pathology Plasma Cells - pathology telomere Telomere - ultrastructure telomere shortening telomeric associations terminal restriction fragments
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