DNA double-strand break repair from head to tail

DNA double-strand break repair is a complex process that requires multiple enzymatic and structural activities to rejoin or repair the broken DNA ends using one of several repair pathways. These enzymatic and structural activities include end detection, end processing and alignment of DNA ends. Rece...

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Bibliographische Detailangaben
Veröffentlicht in:	Current Opinion in Structural Biology 2002-02, Vol.12 (1), p.115-122
Hauptverfasser:	Hopfner, Karl-Peter, Putnam, Christopher D, Tainer, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Antigens, Nuclear Archaeal Proteins - chemistry Archaeal Proteins - physiology DNA - metabolism DNA damage DNA Helicases DNA ligase IV DNA Repair - physiology DNA-Binding Proteins - chemistry DNA-Binding Proteins - physiology double-strand break repair Endodeoxyribonucleases - chemistry Endodeoxyribonucleases - physiology Exodeoxyribonucleases - chemistry Exodeoxyribonucleases - physiology homologous recombination Ku Autoantigen Ku70 protein Ku70/80 Ku80 protein Mre11 Mre11 protein nonhomologous end joining Nuclear Proteins - chemistry Nuclear Proteins - physiology Protein Conformation Rad50 Rad50 protein repair Saccharomyces cerevisiae Proteins Xrcc4 Xrcc4 protein
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