T-Cell Responses to HLA-A0201 Immunodominant Peptides Derived from α-Fetoprotein in Patients with Hepatocellular Cancer

Purpose: An existing immunological paradigm is that high concentrations of soluble protein contribute to the maintenance of peripheral tolerance/ignorance to self protein. We tested this hypothesis in a clinical immunotherapy trial using class I-restricted peptide epitopes derived from α-fetoprotein...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical cancer research 2003-12, Vol.9 (16), p.5902-5908
Hauptverfasser:	BUTTERFIELD, Lisa H, RIBAS, Antoni, ECONOMOU, James S, MENG, Wilson S, DISSETTE, Vivian B, AMARNANI, Saral, VU, Huong T, SEJA, Elisabeth, TODD, Karen, GLASPY, John A, MCBRIDE, William H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged alpha-Fetoproteins - immunology Antigen Presentation - genetics Antineoplastic agents Biological and medical sciences Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - secondary Carcinoma, Hepatocellular - therapy Enzyme-Linked Immunosorbent Assay Freund's Adjuvant - administration & dosage Freund's Adjuvant - immunology HLA-A Antigens - immunology HLA-A2 Antigen Humans Immunotherapy Interferon-gamma - metabolism Lung Neoplasms - immunology Lung Neoplasms - secondary Lung Neoplasms - therapy Medical sciences Middle Aged Pharmacology. Drug treatments Pilot Projects T-Lymphocytes - immunology T-Lymphocytes, Cytotoxic - immunology Vaccines, Subunit - administration & dosage Vaccines, Subunit - genetics Vaccines, Subunit - immunology Vaccines, Subunit - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!