A new strategy for mannose-binding lectin gene haplotyping

The mannose‐binding lectin 2 (MBL2) gene is polymorphic and codes for a protein with an important role in the innate immune response, whose variants have been associated with a great number of diseases. Point variations have been described in the 5′ regulatory region at positions –550 (MBL2*H or *L)...

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Veröffentlicht in:	Human mutation 2002-03, Vol.19 (3), p.296-306
Hauptverfasser:	Boldt, Angelica Beate Winter, Petzl-Erler, Maria Luiza
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute-Phase Proteins - genetics Base Sequence - genetics Brazil Carrier Proteins - genetics DNA - blood genotype haplotype Haplotypes - genetics Humans Lectins - genetics Leukocytes, Mononuclear - chemistry Mannose - metabolism Mannose-Binding Lectin - analogs & derivatives mannose-binding lectin 2 Mannose-Binding Lectins MBL2 Molecular Sequence Data mutation detection Oligonucleotide Probes - genetics PCR-SSOP PCR-SSP Polymerase Chain Reaction - methods Sequence Alignment - methods
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