Synthesis of 2,2′-Dihydroxybisphenols and Antiviral Activity of Some Bisphenol Derivatives

New diphenylmethane-type 2,2′-dihydroxybisphenols (5a—d) were prepared regioselectively in good yields. We evaluated the antiviral activity of some bisphenol derivatives synthesized by the plaque reduction assay. Most of the compounds showed significant antiviral activity and the 4,4′-dihydroxybisph...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2002, Vol.50(2), pp.298-300
Hauptverfasser:	Sumoto, Kunihiro, Mibu, Nobuko, Yokomizo, Kazumi, Uyeda, Masaru
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-HSV-1 Antibiotics. Antiinfectious agents. Antiparasitic agents antiviral activity Antiviral agents Antiviral Agents - chemical synthesis Antiviral Agents - pharmacology Biological and medical sciences bisarylation bisphenol Medical sciences Pharmacology. Drug treatments Phenols - chemical synthesis Phenols - pharmacology plaque reduction assay sonication
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