Quantification of Adenovirus DNA in Plasma for Management of Infection in Stem Cell Graft Recipients
We used a real-time polymerase chain reaction method for quantification of adenovirus to monitor the dynamics of viral DNA load in plasma in pediatric stem-cell graft recipients. Two cases are described to demonstrate that detection and quantification of the adenovirus DNA load at regular intervals...
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| Veröffentlicht in: | Clinical infectious diseases 2002-03, Vol.34 (6), p.864-867 |
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| container_end_page | 867 |
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| container_issue | 6 |
| container_start_page | 864 |
| container_title | Clinical infectious diseases |
| container_volume | 34 |
| creator | Lankester, A. C. van Tol, M. J. D. Claas, E. C. J. Vossen, J. M. Kroes, A. C. M. |
| description | We used a real-time polymerase chain reaction method for quantification of adenovirus to monitor the dynamics of viral DNA load in plasma in pediatric stem-cell graft recipients. Two cases are described to demonstrate that detection and quantification of the adenovirus DNA load at regular intervals may be important to document the stage of adenovirus infection, to make decisions on clinical intervention, and to accurately monitor the response to antiviral therapy. |
| doi_str_mv | 10.1086/339073 |
| format | Article |
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M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantification of Adenovirus DNA in Plasma for Management of Infection in Stem Cell Graft Recipients</atitle><jtitle>Clinical infectious diseases</jtitle><stitle>Clinical Infectious Diseases</stitle><addtitle>Clinical Infectious Diseases</addtitle><date>2002-03-15</date><risdate>2002</risdate><volume>34</volume><issue>6</issue><spage>864</spage><epage>867</epage><pages>864-867</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>We used a real-time polymerase chain reaction method for quantification of adenovirus to monitor the dynamics of viral DNA load in plasma in pediatric stem-cell graft recipients. 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| ispartof | Clinical infectious diseases, 2002-03, Vol.34 (6), p.864-867 |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Adenoviridae - genetics Adenoviridae - physiology Adenovirus Infections, Human - drug therapy Adenoviruses Antivirals Biological and medical sciences Blood plasma Bone marrow Brief Reports Child DNA, Viral - blood Drug Monitoring Hematopoietic Stem Cell Transplantation Human viral diseases Humans Infections Infectious diseases Male Medical sciences Miscellaneous Pediatrics Polymerase Chain Reaction Quantification Symptoms Transplants Viral diseases Viral Load Viruses |
| title | Quantification of Adenovirus DNA in Plasma for Management of Infection in Stem Cell Graft Recipients |
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