The B12/23 Restriction Is Critically Dependent on Recombination Signal Nonamer and Spacer Sequences

Ag receptor variable region gene assembly is initiated through the formation of a synaptic complex which minimally includes the recombination-activating gene (RAG) 1/2 proteins and a pair of recombination signals (RSs) flanking the recombining gene segments. RSs are composed of conserved heptamer an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 2003-12, Vol.171 (12), p.6604-6610
Hauptverfasser:	Hughes, Maureen M, Tillman, Robert E, Wehrly, Tara D, White, J. Michael, Sleckman, Barry P
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions - chemistry 5' Untranslated Regions - genetics Animals Antibody Diversity - genetics Base Sequence Cell Differentiation - genetics Cell Differentiation - immunology Cell Line CHO Cells Cricetinae DNA, Intergenic - chemistry DNA, Intergenic - genetics DNA-Binding Proteins - genetics Extrachromosomal Inheritance - genetics Extrachromosomal Inheritance - immunology Gene Rearrangement, beta-Chain T-Cell Antigen Receptor Genetic Markers Homeodomain Proteins - genetics Immunoglobulin J-Chains - genetics Immunoglobulin Variable Region - genetics Mice Mice, Transgenic Recombination, Genetic RNA Processing, Post-Transcriptional - genetics RNA Processing, Post-Transcriptional - immunology T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!