Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum

Purification of TSH receptor autoantibodies (TRAb) from the serum of patients with Graves’ disease (GD) might help to elucidate the nature of these disease causing autoantibodies. We describe here for the first time the successful affinity purification of human TRAb. Affinity purification was perfor...

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Veröffentlicht in:	Molecular and cellular endocrinology 2003-12, Vol.212 (1), p.73-79
Hauptverfasser:	Morgenthaler, Nils G., Minich, Waldemar B., Willnich, Marita, Bogusch, Thomas, Hollidt, Jörg M., Weglöhner, Wolfgang, Lenzner, Cornelia, Bergmann, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantibodies - blood Autoantibodies - isolation & purification Cattle Chromatography, Affinity Graves Disease - blood Graves Disease - immunology Humans Immunoglobulin G - blood Immunoglobulin G - isolation & purification K562 Cells Receptors, Thyrotropin - genetics Receptors, Thyrotropin - immunology Recombinant Proteins - genetics Recombinant Proteins - immunology Thyroid blocking antibodies Thyroid stimulating antibodies TSH receptor autoantibodies
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