Myc pathways provoking cell suicide and cancer

A paradox for the cancer biology field has been the revelation that oncogenes, once thought to simply provide advantages to a cancer cell, actually put it at dire risk of cell suicide. Myc is the quintessential oncogene in this respect, as in normal cells it is required for cell cycle traverse, wher...

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Veröffentlicht in:	Oncogene 2003-12, Vol.22 (56), p.9007-9021
Hauptverfasser:	Nilsson, Jonas A, Cleveland, John L
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Apoptosis Cancer Cell Biology Cell cycle Cell death Feedback Gene Expression Regulation Genes, bcl-2 Genes, myc Genes, p53 Human Genetics Humans Hypotheses Internal Medicine Kinases Medicine Medicine & Public Health Mitochondria - metabolism Myc protein Neoplasms - genetics Oncology Receptors, Tumor Necrosis Factor review Signal Transduction Tumorigenesis
Online-Zugang:	Volltext
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