Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity

The aorta-gonads-mesonephros (AGM) region autonomously generates the first adult repopulating hematopoietic stem cells (HSCs) in the mouse embryo. HSC activity is initially localized to the dorsal aorta and mesenchyme (AM) and vitelline and umbilical arteries. Thereafter, HSC activity is found in th...

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Veröffentlicht in:	Blood 2002-02, Vol.99 (4), p.1183-1189
Hauptverfasser:	Oostendorp, Robert A.J., Harvey, Kirsty N., Kusadasi, Nuray, de Bruijn, Marella F.T.R., Saris, Chris, Ploemacher, Rob E., Medvinsky, Alexander L., Dzierzak, Elaine A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Aorta - cytology Aorta - embryology Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction Cell Communication Cell differentiation, maturation, development, hematopoiesis Cell physiology Clone Cells - cytology Coculture Techniques - methods Coculture Techniques - standards Digestive System - cytology Digestive System - embryology Fundamental and applied biological sciences. Psychology Gonads - cytology Gonads - embryology Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - cytology Liver - cytology Liver - embryology Medical sciences Mesonephros - cytology Mesonephros - embryology Mice Mice, Transgenic Molecular and cellular biology Stromal Cells - cytology Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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