Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease
We describe a case of malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease. A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the...
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| Veröffentlicht in: | Journal of gastroenterology 2002-01, Vol.37 (1), p.59-67 |
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| creator | Fujisawa, Takashi Osuga, Tatsuya Maeda, Mitsuo Sakamoto, Norikazu Maeda, Tetsuo Sakaguchi, Kazuhiko Onishi, Yutaka Toyoda, Masanori Maeda, Hiroaki Miyamoto, Katsufumi Kawaraya, Nobuaki Kusumoto, Chosei Nishigami, Takashi |
| description | We describe a case of malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease. A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the second part of the duodenum. Contrast-enhanced computed tomography showed a heterogeneous low-density tumor, measuring 20 x 15 mm, in the head of the pancreas, and metastatic lymphadenopathy. Angiography showed faint tumor staining without encasement or apparent increase in vascularity. Pancreatoduodenectomy was performed. Macroscopically, there was a solid tumor, measuring 20 x 18 mm, in the head of the pancreas. Histologically, a malignant endocrine tumor was shown, with direct invasion to the duodenum, and lymph node metastases. This is the thirteenth case of pancreatic malignant tumor and the fourth case of pancreatic endocrine tumor associated with von Recklinghausen's disease reported in the world literature. |
| doi_str_mv | 10.1007/s535-002-8135-x |
| format | Article |
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A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the second part of the duodenum. Contrast-enhanced computed tomography showed a heterogeneous low-density tumor, measuring 20 x 15 mm, in the head of the pancreas, and metastatic lymphadenopathy. Angiography showed faint tumor staining without encasement or apparent increase in vascularity. Pancreatoduodenectomy was performed. Macroscopically, there was a solid tumor, measuring 20 x 18 mm, in the head of the pancreas. Histologically, a malignant endocrine tumor was shown, with direct invasion to the duodenum, and lymph node metastases. This is the thirteenth case of pancreatic malignant tumor and the fourth case of pancreatic endocrine tumor associated with von Recklinghausen's disease reported in the world literature.</description><identifier>ISSN: 0944-1174</identifier><identifier>EISSN: 1435-5922</identifier><identifier>DOI: 10.1007/s535-002-8135-x</identifier><identifier>PMID: 11824803</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Aged ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Combined Modality Therapy ; Duodenal Neoplasms - diagnosis ; Duodenal Neoplasms - therapy ; Duodenoscopy ; Endocrine Gland Neoplasms - complications ; Endocrine Gland Neoplasms - diagnosis ; Endocrine Gland Neoplasms - pathology ; Endocrine Gland Neoplasms - therapy ; Female ; Humans ; Lymphatic Metastasis ; Neoplasm Invasiveness ; Neurofibromatosis 1 - complications ; Pancreatic Neoplasms - complications ; Pancreatic Neoplasms - diagnosis ; Pancreatic Neoplasms - pathology ; Pancreatic Neoplasms - therapy ; Pancreaticoduodenectomy</subject><ispartof>Journal of gastroenterology, 2002-01, Vol.37 (1), p.59-67</ispartof><rights>Springer-Verlag Tokyo 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-b3a933d9349938cae285a06cd3767d934d78dd0697a587378ed91d82a5e6b3493</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11824803$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fujisawa, Takashi</creatorcontrib><creatorcontrib>Osuga, Tatsuya</creatorcontrib><creatorcontrib>Maeda, Mitsuo</creatorcontrib><creatorcontrib>Sakamoto, Norikazu</creatorcontrib><creatorcontrib>Maeda, Tetsuo</creatorcontrib><creatorcontrib>Sakaguchi, Kazuhiko</creatorcontrib><creatorcontrib>Onishi, Yutaka</creatorcontrib><creatorcontrib>Toyoda, Masanori</creatorcontrib><creatorcontrib>Maeda, Hiroaki</creatorcontrib><creatorcontrib>Miyamoto, Katsufumi</creatorcontrib><creatorcontrib>Kawaraya, Nobuaki</creatorcontrib><creatorcontrib>Kusumoto, Chosei</creatorcontrib><creatorcontrib>Nishigami, Takashi</creatorcontrib><title>Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease</title><title>Journal of gastroenterology</title><addtitle>J Gastroenterol</addtitle><description>We describe a case of malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease. A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the second part of the duodenum. Contrast-enhanced computed tomography showed a heterogeneous low-density tumor, measuring 20 x 15 mm, in the head of the pancreas, and metastatic lymphadenopathy. Angiography showed faint tumor staining without encasement or apparent increase in vascularity. Pancreatoduodenectomy was performed. Macroscopically, there was a solid tumor, measuring 20 x 18 mm, in the head of the pancreas. Histologically, a malignant endocrine tumor was shown, with direct invasion to the duodenum, and lymph node metastases. 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Academic</collection><collection>ComDisDome</collection><jtitle>Journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fujisawa, Takashi</au><au>Osuga, Tatsuya</au><au>Maeda, Mitsuo</au><au>Sakamoto, Norikazu</au><au>Maeda, Tetsuo</au><au>Sakaguchi, Kazuhiko</au><au>Onishi, Yutaka</au><au>Toyoda, Masanori</au><au>Maeda, Hiroaki</au><au>Miyamoto, Katsufumi</au><au>Kawaraya, Nobuaki</au><au>Kusumoto, Chosei</au><au>Nishigami, Takashi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease</atitle><jtitle>Journal of gastroenterology</jtitle><addtitle>J Gastroenterol</addtitle><date>2002-01</date><risdate>2002</risdate><volume>37</volume><issue>1</issue><spage>59</spage><epage>67</epage><pages>59-67</pages><issn>0944-1174</issn><eissn>1435-5922</eissn><abstract>We describe a case of malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease. A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the second part of the duodenum. Contrast-enhanced computed tomography showed a heterogeneous low-density tumor, measuring 20 x 15 mm, in the head of the pancreas, and metastatic lymphadenopathy. Angiography showed faint tumor staining without encasement or apparent increase in vascularity. Pancreatoduodenectomy was performed. Macroscopically, there was a solid tumor, measuring 20 x 18 mm, in the head of the pancreas. Histologically, a malignant endocrine tumor was shown, with direct invasion to the duodenum, and lymph node metastases. This is the thirteenth case of pancreatic malignant tumor and the fourth case of pancreatic endocrine tumor associated with von Recklinghausen's disease reported in the world literature.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>11824803</pmid><doi>10.1007/s535-002-8135-x</doi><tpages>9</tpages></addata></record> |
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| subjects | Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Combined Modality Therapy Duodenal Neoplasms - diagnosis Duodenal Neoplasms - therapy Duodenoscopy Endocrine Gland Neoplasms - complications Endocrine Gland Neoplasms - diagnosis Endocrine Gland Neoplasms - pathology Endocrine Gland Neoplasms - therapy Female Humans Lymphatic Metastasis Neoplasm Invasiveness Neurofibromatosis 1 - complications Pancreatic Neoplasms - complications Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Pancreaticoduodenectomy |
| title | Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease |
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