Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target

The discovery of the p73 and p63 genes, homologous to p53 tumor suppressor has uncovered a family of transcription factors and widened the scenario of cell cycle control and apoptosis. We have identified a putative p53-responsive element in the human adenosine deaminase (ADA) gene, an important enzy...

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Veröffentlicht in:	Oncogene 2003-11, Vol.22 (54), p.8738-8748
Hauptverfasser:	TULLO, Apollonia, MASTROPASQUA, Giuseppe, BOURDON, Jean Christophe, CENTONZE, Paola, GOSTISSA, Monica, COSTANZO, Antonio, LEVRERO, Massimo, DEL SAL, Giannino, SACCONE, Cecilia, SBISA, Elisabetta
Format:	Artikel
Sprache:	eng
Schlagworte:	ADA gene Adenosine Adenosine deaminase Adenosine Deaminase - genetics Apoptosis Base Sequence Biological and medical sciences Cell cycle Cell Line Deoxyadenosine Deoxyadenosines - metabolism Deoxyadenosines - pharmacology Deoxyribonucleic acid Diverse techniques DNA DNA biosynthesis DNA repair DNA-Binding Proteins - physiology Ectopic expression Enzymes Fundamental and applied biological sciences. Psychology Gene expression Genes, Tumor Suppressor Humans Isoforms Molecular and cellular biology Molecular Sequence Data Nuclear Proteins - physiology p53 Protein p73 protein Pentostatin - pharmacology Proenzymes Proteins Regulatory sequences RNA, Messenger - analysis Transcription factors Transcriptional Activation Transfection Tumor Protein p73 Tumor suppressor genes Tumor Suppressor Protein p53 - physiology Tumor Suppressor Proteins Tumors
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