Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?
Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD). Methods: 32 patients with suspected malignant superfi...
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| Veröffentlicht in: | European journal of radiology 2003-12, Vol.48 (3), p.252-257 |
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| container_title | European journal of radiology |
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| creator | Schulte-Altedorneburg, Gernot Demharter, Johannes Linné, Renate Droste, Dirk W. Bohndorf, Klaus Bücklein, Wolfgang |
| description | Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD).
Methods: 32 patients with suspected malignant superficial lymph node enlargement prospectively underwent standardised ultrasound examinations using B-mode sonography and native and contrast-enhanced CCDS and PD immediately before biopsy. Solbiati-Index (longitudinal–transverse diameter ratio) and intranodal flow patterns by using different vascularisation types were assessed. Histological and sonographical findings were correlated.
Results: 27 malignant and 5 benign lymph nodes were found. Solbiati-Index was lower in malignant lymph nodes than in benign nodes (mean 1.5 vs. 2.4,
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| doi_str_mv | 10.1016/S0720-048X(03)00076-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71427714</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0720048X03000767</els_id><sourcerecordid>71427714</sourcerecordid><originalsourceid>FETCH-LOGICAL-c391t-437c41029ccad2b57d789e4333dd6a7d541d290bf6b31426653b2b5a14daab393</originalsourceid><addsrcrecordid>eNqFkc1u1DAUhS0EotPCI4C8AcEiYMdOPFlVVVt-pEosAImddWPfzBg5drCTQfMIvDWezogu2fh68R1fn3MIecHZO854-_4rUzWrmFz_eMPEW8aYaiv1iKz4WtWVUrV6TFb_kDNynvPPAjWyq5-SMy7bpuayXpE_NxEzXfycIMclWGpiONxnChsMM3XjlOIO6bxFah1sQsyzM3QHfkEah4L7uCQKRTnF35joTZwmX2aOIW4STNs9dYHmZcI0OOPAU78fpy0N0SLF4CFtcCybLp-RJwP4jM9P84J8_3D77fpTdffl4-frq7vKiI7PlRTKSM7qzhiwdd8oq9YdSiGEtS0o20hu6471Q9uL4rBtG9EXDLi0AL3oxAV5fXy3GPu1YJ716LJB7yFgXLJWRaXKUcDmCJoUc0446Cm5EdJec6YPHej7DvQhYM2Evu9Aq6J7eVqw9CPaB9Up9AK8OgGQDfghQTAuP3BNMdN0B-7yyGGJY-cw6WwcBoPWJTSzttH95yt_AcCSpok</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71427714</pqid></control><display><type>article</type><title>Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Schulte-Altedorneburg, Gernot ; Demharter, Johannes ; Linné, Renate ; Droste, Dirk W. ; Bohndorf, Klaus ; Bücklein, Wolfgang</creator><creatorcontrib>Schulte-Altedorneburg, Gernot ; Demharter, Johannes ; Linné, Renate ; Droste, Dirk W. ; Bohndorf, Klaus ; Bücklein, Wolfgang</creatorcontrib><description>Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD).
Methods: 32 patients with suspected malignant superficial lymph node enlargement prospectively underwent standardised ultrasound examinations using B-mode sonography and native and contrast-enhanced CCDS and PD immediately before biopsy. Solbiati-Index (longitudinal–transverse diameter ratio) and intranodal flow patterns by using different vascularisation types were assessed. Histological and sonographical findings were correlated.
Results: 27 malignant and 5 benign lymph nodes were found. Solbiati-Index was lower in malignant lymph nodes than in benign nodes (mean 1.5 vs. 2.4,
P<0.045). More intranodal flow patterns could be detected after UCA (53 vs. 43) but the number of correctly identified malignant nodes decreased after UCA (26 vs. 24) and the number of correctly identified benign nodes remained constant compared with native CCDS and PD. In 31% of the colour-mode studies, PD was considered to visualise more clearly intranodal vascular flow patterns than CCDS.
Conclusion: despite depicting more intranodal vascular patterns, the use of an ultrasound contrast agent seems not to improve the diagnostic value of CCDS and PD compared with native colour-mode studies in superficial lymph node enlargement.</description><identifier>ISSN: 0720-048X</identifier><identifier>EISSN: 1872-7727</identifier><identifier>DOI: 10.1016/S0720-048X(03)00076-7</identifier><identifier>PMID: 14652142</identifier><identifier>CODEN: EJRADR</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Biopsy, Needle - methods ; Cardiovascular system ; Contrast Media - administration & dosage ; Diagnosis, Differential ; Differential diagnosis ; Doppler sonography ; Echo enhancement ; Female ; Humans ; Image Enhancement - methods ; Investigative techniques, diagnostic techniques (general aspects) ; Lymph node metastasis ; Lymph Nodes - blood supply ; Lymph Nodes - diagnostic imaging ; Lymph Nodes - pathology ; Lymphadenitis - diagnostic imaging ; Lymphadenitis - pathology ; Lymphatic Metastasis ; Lymphoma - diagnostic imaging ; Lymphoma - pathology ; Male ; Medical sciences ; Middle Aged ; Polysaccharides - administration & dosage ; Prospective Studies ; Reactive lymph nodes ; Reproducibility of Results ; Sensitivity and Specificity ; Tuberculosis, Lymph Node - diagnostic imaging ; Ultrasonic investigative techniques ; Ultrasonography, Doppler, Color - methods ; Ultrasound</subject><ispartof>European journal of radiology, 2003-12, Vol.48 (3), p.252-257</ispartof><rights>2003 Elsevier Science Ireland Ltd</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-437c41029ccad2b57d789e4333dd6a7d541d290bf6b31426653b2b5a14daab393</citedby><cites>FETCH-LOGICAL-c391t-437c41029ccad2b57d789e4333dd6a7d541d290bf6b31426653b2b5a14daab393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0720048X03000767$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15333592$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14652142$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schulte-Altedorneburg, Gernot</creatorcontrib><creatorcontrib>Demharter, Johannes</creatorcontrib><creatorcontrib>Linné, Renate</creatorcontrib><creatorcontrib>Droste, Dirk W.</creatorcontrib><creatorcontrib>Bohndorf, Klaus</creatorcontrib><creatorcontrib>Bücklein, Wolfgang</creatorcontrib><title>Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?</title><title>European journal of radiology</title><addtitle>Eur J Radiol</addtitle><description>Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD).
Methods: 32 patients with suspected malignant superficial lymph node enlargement prospectively underwent standardised ultrasound examinations using B-mode sonography and native and contrast-enhanced CCDS and PD immediately before biopsy. Solbiati-Index (longitudinal–transverse diameter ratio) and intranodal flow patterns by using different vascularisation types were assessed. Histological and sonographical findings were correlated.
Results: 27 malignant and 5 benign lymph nodes were found. Solbiati-Index was lower in malignant lymph nodes than in benign nodes (mean 1.5 vs. 2.4,
P<0.045). More intranodal flow patterns could be detected after UCA (53 vs. 43) but the number of correctly identified malignant nodes decreased after UCA (26 vs. 24) and the number of correctly identified benign nodes remained constant compared with native CCDS and PD. In 31% of the colour-mode studies, PD was considered to visualise more clearly intranodal vascular flow patterns than CCDS.
Conclusion: despite depicting more intranodal vascular patterns, the use of an ultrasound contrast agent seems not to improve the diagnostic value of CCDS and PD compared with native colour-mode studies in superficial lymph node enlargement.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle - methods</subject><subject>Cardiovascular system</subject><subject>Contrast Media - administration & dosage</subject><subject>Diagnosis, Differential</subject><subject>Differential diagnosis</subject><subject>Doppler sonography</subject><subject>Echo enhancement</subject><subject>Female</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Lymph node metastasis</subject><subject>Lymph Nodes - blood supply</subject><subject>Lymph Nodes - diagnostic imaging</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphadenitis - diagnostic imaging</subject><subject>Lymphadenitis - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Lymphoma - diagnostic imaging</subject><subject>Lymphoma - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Polysaccharides - administration & dosage</subject><subject>Prospective Studies</subject><subject>Reactive lymph nodes</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Tuberculosis, Lymph Node - diagnostic imaging</subject><subject>Ultrasonic investigative techniques</subject><subject>Ultrasonography, Doppler, Color - methods</subject><subject>Ultrasound</subject><issn>0720-048X</issn><issn>1872-7727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAUhS0EotPCI4C8AcEiYMdOPFlVVVt-pEosAImddWPfzBg5drCTQfMIvDWezogu2fh68R1fn3MIecHZO854-_4rUzWrmFz_eMPEW8aYaiv1iKz4WtWVUrV6TFb_kDNynvPPAjWyq5-SMy7bpuayXpE_NxEzXfycIMclWGpiONxnChsMM3XjlOIO6bxFah1sQsyzM3QHfkEah4L7uCQKRTnF35joTZwmX2aOIW4STNs9dYHmZcI0OOPAU78fpy0N0SLF4CFtcCybLp-RJwP4jM9P84J8_3D77fpTdffl4-frq7vKiI7PlRTKSM7qzhiwdd8oq9YdSiGEtS0o20hu6471Q9uL4rBtG9EXDLi0AL3oxAV5fXy3GPu1YJ716LJB7yFgXLJWRaXKUcDmCJoUc0446Cm5EdJec6YPHej7DvQhYM2Evu9Aq6J7eVqw9CPaB9Up9AK8OgGQDfghQTAuP3BNMdN0B-7yyGGJY-cw6WwcBoPWJTSzttH95yt_AcCSpok</recordid><startdate>20031201</startdate><enddate>20031201</enddate><creator>Schulte-Altedorneburg, Gernot</creator><creator>Demharter, Johannes</creator><creator>Linné, Renate</creator><creator>Droste, Dirk W.</creator><creator>Bohndorf, Klaus</creator><creator>Bücklein, Wolfgang</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20031201</creationdate><title>Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?</title><author>Schulte-Altedorneburg, Gernot ; Demharter, Johannes ; Linné, Renate ; Droste, Dirk W. ; Bohndorf, Klaus ; Bücklein, Wolfgang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-437c41029ccad2b57d789e4333dd6a7d541d290bf6b31426653b2b5a14daab393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle - methods</topic><topic>Cardiovascular system</topic><topic>Contrast Media - administration & dosage</topic><topic>Diagnosis, Differential</topic><topic>Differential diagnosis</topic><topic>Doppler sonography</topic><topic>Echo enhancement</topic><topic>Female</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Lymph node metastasis</topic><topic>Lymph Nodes - blood supply</topic><topic>Lymph Nodes - diagnostic imaging</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphadenitis - diagnostic imaging</topic><topic>Lymphadenitis - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Lymphoma - diagnostic imaging</topic><topic>Lymphoma - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Polysaccharides - administration & dosage</topic><topic>Prospective Studies</topic><topic>Reactive lymph nodes</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Tuberculosis, Lymph Node - diagnostic imaging</topic><topic>Ultrasonic investigative techniques</topic><topic>Ultrasonography, Doppler, Color - methods</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schulte-Altedorneburg, Gernot</creatorcontrib><creatorcontrib>Demharter, Johannes</creatorcontrib><creatorcontrib>Linné, Renate</creatorcontrib><creatorcontrib>Droste, Dirk W.</creatorcontrib><creatorcontrib>Bohndorf, Klaus</creatorcontrib><creatorcontrib>Bücklein, Wolfgang</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schulte-Altedorneburg, Gernot</au><au>Demharter, Johannes</au><au>Linné, Renate</au><au>Droste, Dirk W.</au><au>Bohndorf, Klaus</au><au>Bücklein, Wolfgang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement?</atitle><jtitle>European journal of radiology</jtitle><addtitle>Eur J Radiol</addtitle><date>2003-12-01</date><risdate>2003</risdate><volume>48</volume><issue>3</issue><spage>252</spage><epage>257</epage><pages>252-257</pages><issn>0720-048X</issn><eissn>1872-7727</eissn><coden>EJRADR</coden><abstract>Objective: to analyse whether ultrasound contrast agent (UCA) improves the diagnostic accuracy to differentiate between benign and malignant superficial lymph node enlargement by using colour-coded duplex sonography (CCDS) and power Doppler (PD).
Methods: 32 patients with suspected malignant superficial lymph node enlargement prospectively underwent standardised ultrasound examinations using B-mode sonography and native and contrast-enhanced CCDS and PD immediately before biopsy. Solbiati-Index (longitudinal–transverse diameter ratio) and intranodal flow patterns by using different vascularisation types were assessed. Histological and sonographical findings were correlated.
Results: 27 malignant and 5 benign lymph nodes were found. Solbiati-Index was lower in malignant lymph nodes than in benign nodes (mean 1.5 vs. 2.4,
P<0.045). More intranodal flow patterns could be detected after UCA (53 vs. 43) but the number of correctly identified malignant nodes decreased after UCA (26 vs. 24) and the number of correctly identified benign nodes remained constant compared with native CCDS and PD. In 31% of the colour-mode studies, PD was considered to visualise more clearly intranodal vascular flow patterns than CCDS.
Conclusion: despite depicting more intranodal vascular patterns, the use of an ultrasound contrast agent seems not to improve the diagnostic value of CCDS and PD compared with native colour-mode studies in superficial lymph node enlargement.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>14652142</pmid><doi>10.1016/S0720-048X(03)00076-7</doi><tpages>6</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Biological and medical sciences Biopsy, Needle - methods Cardiovascular system Contrast Media - administration & dosage Diagnosis, Differential Differential diagnosis Doppler sonography Echo enhancement Female Humans Image Enhancement - methods Investigative techniques, diagnostic techniques (general aspects) Lymph node metastasis Lymph Nodes - blood supply Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymphadenitis - diagnostic imaging Lymphadenitis - pathology Lymphatic Metastasis Lymphoma - diagnostic imaging Lymphoma - pathology Male Medical sciences Middle Aged Polysaccharides - administration & dosage Prospective Studies Reactive lymph nodes Reproducibility of Results Sensitivity and Specificity Tuberculosis, Lymph Node - diagnostic imaging Ultrasonic investigative techniques Ultrasonography, Doppler, Color - methods Ultrasound |
| title | Does ultrasound contrast agent improve the diagnostic value of colour and power Doppler sonography in superficial lymph node enlargement? |
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