Trypanosoma cruzi surface mucin TcMuc-e2 expressed on higher eukaryotic cells induces human T cell anergy, which is reversible

Chagas' disease is a chronic, debilitating, multisystemic disorder that affects millions of people in Latin America. The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, has a large number of O-glycosylated Thr/Ser/Pro-rich mucin molecules on its surface (TcM...

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Veröffentlicht in:	Glycobiology (Oxford) 2002-01, Vol.12 (1), p.25-32
Hauptverfasser:	Argibay, Pablo F, Di Noia, Javier M, Hidalgo, Alejandra, Mocetti, Esteban, Barbich, Mariana, Lorenti, Alicia S, Bustos, Daniel, Tambutti, Monica, Hyon, Sung H, Frasch, Alberto C C, Sánchez, Daniel O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Division Cercopithecus aethiops Clonal Anergy - physiology Down-Regulation Humans Lymphocyte Activation Mucins - metabolism Mucins - physiology T-Lymphocytes - cytology Trypanosoma cruzi Trypanosoma cruzi - metabolism Vero Cells
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