Total Synthesis of Siphonarin B and Dihydrosiphonarin B

The spirocyclic core of the siphonarins was constructed by a directed cyclization of a linear triketone, prepared using a Sn(II)-mediated aldol coupling and Swern oxidation at C9 and C13. To circumvent a facile retro-Claisen pathway generating a baconipyrone-type ester, a Ni(II)/ Cr(II)-mediated cou...

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Veröffentlicht in:	Organic letters 2002-02, Vol.4 (3), p.391-394
Hauptverfasser:	Paterson, Ian, Chen, David Yu-Kai, Franklin, Alison S
Format:	Artikel
Sprache:	eng
Schlagworte:	Ketones - chemical synthesis Molecular Structure Spiro Compounds - chemical synthesis
Online-Zugang:	Volltext
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