Organization and evolution of multifunctional Ca(2+)/CaM-dependent protein kinase genes

The "multi-functional" Ca(2+) and calmodulin-dependent protein kinase, type II (CaMK-II) is an evolutionarily conserved protein. It has been found as a single gene in the horseshoe crab, marine sponge, sea urchin, nematode, and fruit fly, whereas most vertebrates possess four genes (alpha,...

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Veröffentlicht in:	Gene 2003-12, Vol.322, p.17-31
Hauptverfasser:	Tombes, Robert M, Faison, M Omar, Turbeville, J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - genetics Calcium-Calmodulin-Dependent Protein Kinases - metabolism Evolution, Molecular Gene Expression Regulation, Enzymologic Genes - genetics Humans Molecular Sequence Data Phylogeny Sequence Homology, Amino Acid
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